Abstract
Testicular lymphomas are rare, accounting for only 5% of all testicular tumors. The majority of these tumors are part of the disseminated disease process, and only rarely arise as a primary lesion. Most testicular lymphomas are B-cell lymphomas. Testicular T-cell lymphomas, are rarely detected, but have many subtypes according to the immunohistological feature, and have poor outcome and high relapse rates, even with a localized disease. Herein, 2 cases of testicular T-cell lymphoma, initially manifesting in the testis, are reported, with a review of the clinical features and outcomes.
Figures and Tables
References
1. Zucca E, Conconi A, Mughal TI, Sarris AH, Seymour JF, Vitolo U, et al. Patterns of outcome and prognostic factors in primary large-cell lymphoma of the testis in a survey by the International Extranodal Lymphoma Study Group. J Clin Oncol. 2003. 21:20–27.
2. Chan JK, Tsang WY, Lau WH, Cheung MM, Ng WF, Yuen WC, et al. Aggressive T/natural killer cell lymphoma presenting as testicular tumor. Cancer. 1996. 77:1198–1205.
3. Jaffe ES, Chan JK, Su IJ, Frizzera G, Moris S, Feller AC, et al. Report of the Workshop on nasal and related extranodal angiocentric T/Natural Killer Cell Lymphomas. Definitions, differential diagnosis, and epidemiology. Am J Surg Pathol. 1996. 20:103–111.
4. Güler G, Altinok G, Üner AH, Sunqur A. CD56+ lymphoma presenting as a testicular tumor. Leuk Lymphoma. 1999. 36:207–211.
5. Lee HI, Chang HJ, Chang TJ, Lee KS. Primary T cell lymphoma of the testis. Korean J Urol. 2001. 42:1333–1335.
6. Kim YB, Chang SK, Yang WI, Hahn JS, Koom WS, Shim SJ, et al. Primary NK/T cell lymphoma of the testis. A case report and review of the literature. Acta Haematol. 2003. 109:95–100.
7. Shipp MA. Prognostic factors in aggressive non-Hodgkin's lymphoma: who has "high-risk" disease? Blood. 1994. 83:1165–1173.
8. Hasselblom S, Ridell B, Wedel H, Norrby K, Sender Baum M, Ekman T. Testicular lymphoma: a retrospective, population-based, clinical and immunohistochemical study. Acta Oncol. 2004. 43:758–765.