We report the case of a 64-year-old female patient with an undifferentiated carcinoma involving the pancreatic head in whom hepatic metastasis and encasement of the portal and superior mesenteric veins had occurred. Ultrasound demonstrated a round well-defined hypoechoic mass with increased color Doppler flow signals at the periphery, while CT revealed a heterogeneously enhanced mass with a less attenuated central portion and rim enhancement of the pancreatic head.