PURPOSE: To evaluate the CT findings and clinical significance of colonic edema in liver cirrhosis. MATERIALS AND METHODS: We retrospectively reviewed the CT scans of 221 cases of clinically diagnosed liver cirrhosis in 173 patients. In 30 of these [23 men and six women aged between 35 and 67 (mean, 54) years], colonic edema was present. We evaluated its distribution (ascending, transverse or descending colon), analysed serum albumin and bilirubin levels, and in both the colonic edema and non-colonic edema group, determined whether ascites was present. Thus, we sought correlation between the presence of colonic edema, the severity of liver cirrhosis, and each parameter. RESULTS: CT revealed colonic edema in 30 of 221 cases (14 %). Of the 30, 13 cases (43 %) were diffuse colonic edema and 17 (57 %) were regional edema. Among these 17 cases, 12 (71 %) were seen only in the ascending colon, while five (29 %) were seen in both the ascending and transverse colon. In the group with colonic edema, the mean level of serum albumin was 2.6 g/dl, and that of serum bilirubin was 4.9 mg/dl; 20 patients ( 67 %) had ascites. In the group without colonic edema, mean levels of serum albumin and serum bilirubin were 3.0 g/dl and 4.1 mg/dl, respectively ; 43 patients (30 %) had ascites. There was no significant statistical difference in serum albumin and bilirubin levels between the colonic edema and non-colonic edema group (p>0.05), though ascites was more common among the former group. CONCLUSION: In cases of liver cirrhosis, CT evidence of colonic edema is not uncommon. The ascending colon is most frequently involved, though disease severity does not vary significantly according to site. When CT reveals the presence of colonic edema, further diagnostic evaluation is not necessary if there is no evidence of clinical symptoms.