Caudal regression syndrome is a rare congenital anomaly, which results from a developmental failure of thecaudal mesoderm during the fetal period. We present a case of caudal regression syndrome composed of a spectrum ofanomalies including sirenomelia, dysplasia of the lower lumbar vertebrae, sacrum, coccyx and pelvic bones,genitourinary and anorectal anomalies, and dysplasia of the lung, as seen during infantography and MR imaging.