MRI Findings of Extramedullary Hematopoiesis of the Spleen in Patient with Idiopathic Myelofibrosis : 2 Case Report1

Hyoung Seuk Kim; Cheol Min Park; In Ho Cha; Aeree Kim; Moon-Gyu Lee; Yong Ho Auh

doi:10.3348/jkrs.1998.38.3.507

Journal List > J Korean Radiol Soc > v.38(3) > 1068152

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Kim, Park, Cha, Kim, Lee, and Auh: MRI Findings of Extramedullary Hematopoiesis of the Spleen in Patient with Idiopathic Myelofibrosis : 2 Case Report1

Case-Report

J Korean Radiol Soc 1998;38(3):507-510.

Published online: 18 December 1998

DOI: https://doi.org/10.3348/jkrs.1998.38.3.507

MRI Findings of Extramedullary Hematopoiesis of the Spleen in Patient with Idiopathic Myelofibrosis : 2 Case Report¹

Hyoung Seuk Kim, M.D., Cheol Min Park, M.D., In Ho Cha, M.D., Aeree Kim, M.D.², Moon-Gyu Lee, M.D.³, Yong Ho Auh, M.D.³

¹Department of Radiology, Korea University College of Medicine

²Department of Anatomic Pathology, Korea University College of Medicine

³Department of Diagnostic Radiology, Asan Medical Center, University of Ulsan Medical College

Address reprint requests to : Hyoung Seuk Kim, M.D., Department of Diagnostic Radiology, Guro Hospital Korea University Medical Center, tt 80 Guro- Dong, Guro-Ku, Seoul, Korea 152-050 Tel. 818-6183 Fax. 863-9282

Received 20 August 1997 Accepted 9 December 1997

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

MRI findings of extramedullary hematopoiesis of the spleen have not been described in the literature. We report the MRI features of this condition, as seen in two patients and confirmed by fine needle biopsy. Three small masses(<3cm) were isointense on T1WI, hyperintense on T2WI, and enhanced after the injection of gadolinium. Two 6cm-sized masses were hypointense on both T1WI and T2WI, and showed no contrast enhancement.

Keywords: Spleen, MR, Spleen, diseases

REFERENCES

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Fig. 1.

Extramedullary hematopoiesis of the spleen in 38-year-old man with myelofibrosis. A. Tl-weighted image (TR/TE, 600msec/l7 msec) shows a 6cm sized, slightly low signal intensity lesion(arrows), in the lower pole of enlarged spleen. B. Same lesion in the lower pole is noted as low signal intensity on T2-weighted image (TR/tE, 3300msec/140msec). C. T2-weighted image (TR/TE, 3300msec/140msec) shows two lesions of high signal intensity with diameters less than 3cm in the upper pole of spleen. Another small lesion of high signal intensity was also noted (not shown). D. Post-Gadolinium enhanced Tl-weighted image (TR/TE, 600msec/l7msec) shows contrast enhancement of the upper pole lesions. Lower pole lesion was not enhanced (not shown).

Fig. 2.

Extramedullary hematopoiesis of the spleen in 69-year-old man with myelofibrosis. A. Tl-weighted image (TR/TE, 500msec/20mse) shows 6cm-sized focal lesion of low signal intensity. B. This lesion is demonstrated as low signal intensity on Τ2-weighted image (TR/TE, 2000msec/80msec).

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