Behcet's disease, though originally described as a triad of oral and genital aphthous ulcers and inflammatory, occular lesion, has had several new elements added to its description. The gastrointestinal manifestation of Behcet's disease including colitis and esophageal ulceration has been recognized in recent years. Four cases of Behcet's disease with colitis and one case with esophageal ulceration are presented and characteristic radiographic findings are described. In colitis and ulcerative esophagitis in Behcet's disease, the ulcers show collar-button appearance and tend to perforate at multiple sites, producing panperitonitis and esophagobronchial fistula, and intervening mucosa is usually normal.