Journal List > J Rheum Dis > v.25(1) > 1064378

Kim, Im, Kang, Kim, Park, Bae, Nam, and Kang: Bilateral Involvement of Juvenile Temporal Arteritis Associated with Kimura Disease

Abstract

Juvenile temporal arteritis (JTA) is a localized nodular arteritis confined to the temporal artery without evidence of systemic inflammation, and it occurs mainly in patients younger than 50 years. From the first case report, the pathological features of JTA have been suspected to be the morphological equivalent of Kimura disease (KD), which has been supported further by the concurrent cases of JTA with KD. We present the first case of bilateral JTA accompanying KD, which was confirmed by histological and ultrasound evaluations and supports the hypothesis that JTA is a manifestation of KD. The un-excised JTA lesion was resolved completely after corticosteroid therapy with no recurrence.

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Figure 1.
Gross appearance (A: left, B: right), computed tomographic angiography (C) and Doppler ultrasound images (D: short axis, E: long axis) of the nodular lesion on the left superficial temporal artery.
jrd-25-65f1.tif
Figure 2.
Inguinal and antecubital lymph nodes showed markedly increased lymphoid follicles with germinal centers and exuber-ant eosinophilic infiltrations, which is compatible with Kimura disease (H&E, A: ×40; B: ×200; C: ×400).
jrd-25-65f2.tif
Figure 3.
Biopsy of the superficial temporal artery lesions (H&E, A: ×40; B: ×100) showed intravascular proliferating structures, with eosinophilic infiltrations covered by endothelial linings (C: CD 34, ×200) and intramural and perivascular inflammatory lesions.
jrd-25-65f3.tif
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