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Abstract
Cytomegalovirus (CMV), a member of the human herpesvirus group, causes severe disease in immunocompromised patients. In particular, CMV pneumonia can be a life-threatening disease to patients taking immunosuppressive drugs. The radiographic manifestations of CMV are variable and may consist of reticular or reticulonodular patterns, ground-glass opacities, air-space consolidations, or mixed patterns. A cavitary lesion in pneumonia associated with CMV infection is extremely rare. Herein we report on a case of CMV pneumonia which presented with a cavitary lesion and was treated successfully in a systemic lupus erythematosus patient who was taking immunosuppressive drugs.
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Figure 1.
Chest plain radiography shows a large cavitary mass like lesion in the right upper lung field (arrow).
Figure 2.
Chest computed tomography with coronal reformatted image shows a large cavitary mass like lesion in the right upper lobe.
Figure 3.
(A) The irregularly dilated alveoli showed mononuclear inflammatory cell infiltration in the interstitium and multiple intranuclear cytomegalovirus inclusions in the alveolar pneumonocytes (arrows) (H&E, ×400). (B) Immunohistochemistry (IHC) with an-ti-cytomegalovirus (CMV) confirmed the CMV infected pneumonocytes with intranuclear inclusions (arrows) (IHC, ×400).
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