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Abstract
Cytomegalovirus (CMV), a member of the human herpesvirus group, causes severe disease in immunocompromised patients. In particular, CMV pneumonia can be a life-threatening disease to patients taking immunosuppressive drugs. The radiographic manifestations of CMV are variable and may consist of reticular or reticulonodular patterns, ground-glass opacities, air-space consolidations, or mixed patterns. A cavitary lesion in pneumonia associated with CMV infection is extremely rare. Herein we report on a case of CMV pneumonia which presented with a cavitary lesion and was treated successfully in a systemic lupus erythematosus patient who was taking immunosuppressive drugs.
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 | Figure 1.Chest plain radiography shows a large cavitary mass like lesion in the right upper lung field (arrow). |
 | Figure 2.Chest computed tomography with coronal reformatted image shows a large cavitary mass like lesion in the right upper lobe. |
 | Figure 3.(A) The irregularly dilated alveoli showed mononuclear inflammatory cell infiltration in the interstitium and multiple intranuclear cytomegalovirus inclusions in the alveolar pneumonocytes (arrows) (H&E, ×400). (B) Immunohistochemistry (IHC) with an-ti-cytomegalovirus (CMV) confirmed the CMV infected pneumonocytes with intranuclear inclusions (arrows) (IHC, ×400). |
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