Journal List > J Rheum Dis > v.22(2) > 1064178

Lee, Park, Nam, Shim, and Kang: Idiopathic Retroperitoneal Fibrosis Associated with Rheumatoid Arthritis in a Patient with Concomitant Chronic B Viral Hepatitis

Abstract

Retroperitoneal fibrosis (RPF) is a rare, progressive disease characterized by chronic non specific inflammation of the retroperitoneum. Although the pathogenesis of idiopathic retroperitoneal fibrosis (IRF) remains unclear, IRF has been reported in association with autoimmune disorders. However, few cases of IRF associated with rheumatoid arthritis (RA) have been reported. We experienced a rare case of IRF in a patient with RA and chronic B viral hepatitis. A 39-year-old Korean man with RA and hepatitis B was referred to our hospital due to left hydronephrosis. An abdominal computed tomography (CT) scan and magnetic resonance imaging (MRI) showed a diffuse infiltrating retroperitoneal mass around the abdominal aorta and left ureter. The patient underwent intraureteral stent insertion and was treated with corticosteroid. Three months later, the follow up abdominal CT showed that the retroperitoneal mass had decreased in size. Herein, we report the first case of coexistent IRF, RA, and chronic B viral hepatitis with a literature review.

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Figure 1.
(A) Abdominal computed tomography shows a diffuse infiltrating soft tissue mass (about 5.0×2.5×10.3 cm sized) extending from the lower abdominal aorta to the level of the iliac bifurcation and left ureteral obstruction (arrow). (B) Atrophic change on left kidney (arrowhead).
jrd-22-123f1.tif
Figure 2.
(A) The lesion reveals a fibrous proliferation with broad anatomizing bands of collagen. Occasionally lymphoid aggregates are noted (arrow) (H&E, ×40). (B) Fibrous proliferation with sclerotic collagen bands (H&E, ×200).
jrd-22-123f2.tif
Figure 3.
The retroperitoneal mass was decreased at the follow-up abdominal computed tomography (arrow).
jrd-22-123f3.tif
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