Journal List > J Rheum Dis > v.21(2) > 1064168

J Rheum Dis. 2014 Apr;21(2):87-90. Korean.
Published online April 30, 2014.
Copyright © 2014 by The Korean College of Rheumatology
A Case of Condyloma Acuminata in a Virgin Systemic Lupus Erythematosus Patient
Yong Jun Kim, Chang Kyoo Byon, Eun Seok Kim, Hyun Jeong Kim, Il Hwan Jeong, Won Suk An, Sang Yeob Lee, Sung Won Lee and Won Tae Chung
Department of Internal Medicine, College of Medicine, Dong-A University, Busan, Korea.

Corresponding to: Won Tae Chung, Department of Internal Medicine, College of Medicine, Dong-A University, 1, Dongdaesin-dong 3ga, Seo-gu, Busan 602-715, Korea. Email:
Received February 20, 2013; Revised June 17, 2013; Accepted June 18, 2013.

This is a Free Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.


Anogenital infection with human papillomavirus (HPV) is one of the most common sexually transmitted infections worldwide. The majority of HPV infections are transient and subclinical, with subsequent clearance by the immune system. However, in some individuals, especially those with impaired immunity, HPV infection may persist and result in condyloma acuminatum, pre-cancerous cervical abnormalities, as well as cervical cancer. Because of the intrinsic immunological aberrations and immunosuppressive treatment, patients with systemic lupus erythematosus (SLE) have higher prevalence of anogenital HPV infection, and SLE itself appears to be a major risk factor for HPV infection. HPV infection is sexually transmitted via genital contact; autogenesis of condyloma acuminatum without sexual contact is rare. In this case, a 27-year old virgin female with SLE was admitted to our clinic, presenting anogenital condyloma acuminata. It report that SLE patient can have a disease of anogenital HPV infection, despite the lack of sexual contact. Therefore, we recommend that patients with SLE have regular gynecological evaluations, in addition to prophylactic HPV vaccinations.

Keywords: Systemic lupus erythematosus; Condylomata acuminata; Human papillomavirus


Figure 1
Multiple, variable sized condyloma accuminata on external genitalia and perianal area.
Click for larger image

Figure 2
Removed multiple, large, exophytic cauliflower-like masses on perianal area.
Click for larger image

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