Journal List > J Rheum Dis > v.21(4) > 1064123

Hwang, Lee, Ryu, Choi, Lee, Kim, Kim, Kim, Lee, and Bang: Diffuse Skeletal Hemangiomatosis Mimicking Sacroiliitis

Abstract

Hemangiomatosis of the skeletal system is a rare disease without specific symptoms and signs. We describe a 20-year-old patient with low back pain, whose plain radiographs of sacroiliac (SI) joint showed irregular sclerotic lesions. The patient was finally confirmed with skeletal hemangiomatosis by magnetic resonance imaging (MRI) and excisional biopsy of the lesion. The present case suggests that if patients with abnormal lesions of the SI joint in the plain radiographs do not have typical inflammatory back pain, advanced imaging is required to make an accurate diagnosis. Our case also emphasizes the importance of MRI and biopsy in establishing the diagnosis.

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Figure 1.
(A) X-ray showing irregular sclerotic lesions of the left SI joint (arrowheads), and sclerotic cystic lesions in the both sacral wing and left ilium (arrows). (B) Sclerotic changes of vertebral endplates in a lumbar spine X-ray. (C) Pelvic bone CT scan showing sclerotic cystic lesions in the sacral wing and left ilium (arrows). (D) MRI of the SI joints showing subchondral, cortical, intramedul-lary osseous cysts (arrows). (E) In the T1 weighted and T2 weighted MRI images of the L-spine, multiple T1 low, T2 high signal intensities are scattered from the T9 to the S3 vertebra. (F) In fat suppression images the lesions appear as high signal intensities, and are markedly enhanced after gadolinium administration. (G) CT scan showing multiple irregularly-shaped fat-containing lesions in the thoracolumbar vertebrae, sacrum, and left iliac bone (arrows) and multiple cystic mass lesions in the spleen (arrowheads).
jrd-21-205f1.tif
Figure 2.
Histologic appearance of a bone lesion (hematoxylin-eosin ×200 (A) and ×400 (B)) shows bony trabecula with some medium-sized abnormal vessels in fatty marrow spaces.
jrd-21-205f2.tif
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