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Abstract
Objective
To evaluate the validity of the Korean version of ASAS-HI in patients with spondyloarthritis in Korea.
Methods
A total of 91 patients were enrolled. We evaluated the validity by calculating the correlation coefficients between the Korean version of ASAS-HI and other clinical parameters, including patient global assessment (PGA), spinal back pain score, Bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis functional index (BASFI), ankylosing spondylitis disease activity score (AS-DAS), work productivity and activity impairment (WPAI) number 5 and number 6, hospital Anxiety and Depression Scale (HADS), health Survey Short-Form 36 (SF-36), and EuroQol visual analogue scale (EQ-5D VAS). Using a Pearson correlation coefficient, the validity was assessed by making a comparison between the correlation of the ASAS HI and clinical parameters in all patients.
Results
The Korean version of ASAS-HI score was correlated with PGA, spinal back pain score, BASDAI, BASFI, AS-DAS, WPAI number 5, WPAI number 6, HADS, and EQ-5D (r=0.331, 0.403, 0.638, 0.500, 0.595, 0.480, 0.573, 0.626, −0.497, p=0.002, ＜0.001, ＜0.001, ＜0.001, ＜0.001, ＜0.001, ＜0.001, and ＜0.001, respectively).
Conclusion
In this study, the clinical effectiveness of the Korean version of ASAS-HI was proved by calculating the correlation with other clinical parameters. The Korean version of ASAS-HI can be used in clinical practice and research to assess the healthy state of spondyloarthritis patients in Korea.
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Table 1.
Baseline demographics and clinical characteristics of subjects
AS: Ankylosing spondylitis, Nr-axial SpA: non-radiographics axial spondyloarthritis, Peripheral SpA: Peripheral spondyloarthritis, PGA: patient's global assessment, KHADS: Korean hospital Anxiety and Depression Scale, KBASDAI: Korean Bath ankylosing spondylitis disease activity index, KBASFI: Korean Bath ankylosing spondylitis functional index, KEQ-5D: Korean EuroQol visual analogue scale, KSF-36: Korean Health Survey Short-Form 36, CRP: C-reactive protein, AS-DAS: Ankylosing spondylitis disease activity score, ASAS-HI: ASAS heath index.
Table 2.
Correlation coefficient between ASAS-HI score and other clinical factors
| Factors | Pearson correlation coefficients ASAS-HI (scores) |
|---|---|
| Age (years) | 0.225* |
| Disease duration (years) | 0.165 |
| Patient's global assessment | 0.331† |
| (0-10 NRS) | |
| Education | −0.005* |
| Disease activity (0-10 NRS) | −0.209† |
| Spinal back pain (0-10 NRS) | 0.403† |
| KBASDAI (scores) | 0.638† |
| KBASFI (scores) | 0.500† |
| CRP (mg/L) | 0.152 |
| AS-DAS (scores) | 0.595† |
| KWPAI, while working (scores) | 0.480† |
| KWPAI, regular activity (scores) | 0.573† |
| KHADS (scores) | 0.626† |
| KSF-36 (scores) | −0.209* |
| KEQ-5D VAS (mm) | −0.497† |
ASAS-HI: ASAS heath index, KBASDAI: Korean Bath ankylosing spondylitis disease activity index, KBASFI: Korean Bath ankylosing spondylitis functional index, CRP: C-reactive protein, AS-DAS: Ankylosing spondylitis disease activity score, KWPAI: Korean work productivity and activity impairment, KHADS: Korean Hospital Anxiety and Depression Scale, KSF-36: Korean Health Survey Short-Form 36, KEQ-5D: Korean EuroQol visual analogue scale
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