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Lee, Kim, Jung, Lee, Kim, Rim, Lee, Kim, Bang, and Lee: A Case of Klinefelter's Syndrome Accompanying with Polymyositis
Case Report
Journal of Rheumatic Diseases

Journal of Rheumatic Diseases 2012; 19(3): 152-155.

Published online: 30 June 2012

DOI: https://doi.org/10.4078/jrd.2012.19.3.152

A Case of Klinefelter's Syndrome Accompanying with Polymyositis

Min Kyu Lee, Byung Sik Kim, Suk Hyun Jung, Gun Hwa Lee, Jin Ok Kim, Dong Hwi Rim, Yu Hwa Lee, Woong Jun Kim, So-Young Bang, Hye-Soon Lee

Division of Rheumatology, Department of Internal Medicine, Hanyang University College of Medicine, Guri Hospital, Guri, Korea.

Corresponding to: Hye-Soon Lee, Division of Rheumatology, Department of Internal Medicine, Hanyang University College of Medicine, Guri Hospital, 249-1, Kyomoon-dong Guri 471-020, Korea. lhsberon@hanyang.ac.kr

Received 30 June 2011       Revised 15 September 2011       Accepted 22 September 2011

Copyright © 2012 by The Korean College of Rheumatology

(free-access):

This is a Free Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Klinefelter's syndrome which is characterized by hypogonadism with karyotype abnormality (47 XXY or 46 XY/47 XXY) in males has been reported to be associated with autoimmune diseases including rheumatoid arthritis and systemic lupus erythematosus. However, Klinefelter's syndrome accompanying with polymyositis has rarely been reported. We report a case of KFS with polymyosits in a 38-year old man for the first time in Korea.

Keywords: Polymyositis, Klinefelter's syndrome, Hypogonadism

Figures and Tables

Figure 1
The thigh MRI shows T2 high signal intensity and enhancement of vastus intermedius, vastus medialis, vastus lateralis, gracilis, semimembranous, and semitensinosus muscle of the both thighs (A, B). These findings are compatible with myositis.
jrd-19-152-g001

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