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Jung, Kim, Byon, Lee, Lee, and Chung: A Cases of Adult Onset Still's Disease with Hemolytic Anemia
Case Report
Journal of Rheumatic Diseases

Journal of Rheumatic Diseases 2012; 19(2): 104-107.

Published online: 30 April 2012

DOI: https://doi.org/10.4078/jrd.2012.19.2.104

A Cases of Adult Onset Still's Disease with Hemolytic Anemia

Jin Kyu Jung, Yong Jun Kim, Chang Kyoo Byon, Sang Yeob Lee, Sung Won Lee, Won Tae Chung

Department of Internal Medicine, College of Medicine, Dong-A University, Pusan, Korea.

Corresponding to: Won Tae Chung, Department of Internal Medicine, College of Medicine, Dong-A University, Dongdaesin-dong 3-ga, Seo-gu, Pusan 602-715, Korea. wtchung@dau.ac.kr

Received 8 August 2011       Accepted 30 August 2011

Copyright © 2012 by The Korean College of Rheumatology

(free-access):

This is a Free Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Adult onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown etiology. AOSD is characterized by fever, arthralgia, salmon-colored skin rash, hepatosplenomegaly and its laboratory abnormalities include leukocytosis, elevated liver enzyme, negative autoantibody, and hyperferritinemia. The clinical course varied and severe complicated conditions, such as hemophagocytic syndrome, and disseminated intravascular coagulation, occurred occasionally. Such a complication is accompanied with hemolytic anemia and lead to be a fatal course. We report the first case of AOSD with hemolytic anemia, which improved with high dose steroid therapy.

Keywords: Adult onset still disease, Hemolytic anemia

Figures and Tables

Figure 1
Peripheral blood shows polychromasia and schistocytes (Wright-Giemsa stain, ×1,000).
jrd-19-104-g001
Figure 2
Bone marrow aspiration shows a slight increase in the number of myeloid precursors. The marrow is slightly hypocellular (Wright-Giemsa stain, ×200).
jrd-19-104-g002
Figure 3
Abdomen CT shows hepatosplenomegaly.
jrd-19-104-g003

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