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Cho, Oh, Han, Sung, Bae, Shon, and Yoon: A Case of Fetal Alcohol Syndrome with Secondary Amenorrhea
Case Report
Journal of Korean Society of Endocrinology

Journal of Korean Society of Endocrinology 2005; 20(5): 524-530.

Published online: 20 October 2005

DOI: https://doi.org/10.3803/jkes.2005.20.5.524

A Case of Fetal Alcohol Syndrome with Secondary Amenorrhea

Yoon Young Cho, Hyo Jin Oh, Seok Jae Han, Sang Hun Sung, Gyu Hwan Bae, Ho Sang Shon, Hyun Dae Yoon

Department of Internal Medicine, School of Medicine, Catholic University of Daegu, Korea.

Received 20 August 2005       Accepted 11 October 2005

Copyright © 2005 Korean Endocrine Society

Abstract

Alcohol ingestion during pregnancy can be damaging to embryonic and fetal development. A specific pattern of malformation, identified as Fetal alcohol syndrome, has been documented in 1~2 of every 1,000 live infant births Fetal alcohol syndrome is characterized by growth deficiency, facial abnormalities, cardiac defects, minor joint and limb abnormalities, as well as central nervous system dysfunction, including microcephaly, mental retardation and abnormal neurobehavioral development. However, there are few reports of fetal alcohol syndrome associated with hormonal abnormality or amenorrhea. Recently, a case of secondary amenorrhea, which developed in a 19-year-old woman with fetal alcohol syndrome, was experienced at our institute, but the exact cause of the amenorrhea was difficulty to find. Herein, this case is reported, with a review of the literature.

Keywords: Fetal alcohol syndrome, Amenorrhea, Hormone

Figures and Tables

Fig. 1
Chromosomal analysis shows normal karyotype (46XX).
jkse-20-524-g001
Fig. 2
Abdominopelvic CT shows that uterus and ovaries are unremarkable.
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Fig. 3
Brain MRI Shows hypogenesis of the corpus callosum with colpocephaly (A) and ectopic neurohypophysis at the pituitary stalk (B).
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Table 1
Diagnostic Criteria for Fetal Alcohol Syndrome and Alcohol-related Effects
jkse-20-524-i001
Table 2
The Results of Combined Pituitary Stimulation Test
jkse-20-524-i002

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