Journal List > J Korean Soc Endocrinol > v.20(5) > 1063820

Kim, Koo, Lee, Kim, Cho, Lee, and Kim: A case of Paraganglioma Arising in the Transverse Mesocolon

Abstract

Herein, a case of a solitary primary paraganglioma arising in the mesentery, found in a hypertensive 70-year-old woman, who presented with nausea and postprandial abdominal discomfort, is reported. Ultrasonography and computed tomography showed a hypervascular mass abutting the second portion of the duodenum. An exploratory laparotomy revealed a 5.5×5.3×5 cm sized mass in the mesentery of the transverse colon, which was histologically proven to be a paraganglioma. No intraoperative hemodynamic changes developed, and the postoperative course was uneventful. To our knowledge, this is the first case of a paraganglioma arising in the mesentery reported in Korea. Considering the unusual locations and the associated operative risk, it is necessary to rule out the possibility of a functioning paraganglioma in the preoperative differential diagnosis of an abdominal mass.

Figures and Tables

Fig. 1
Computed tomography of abdomen.
A 4~5 cm sized, well-enhanced hypervascular mass was detected around the second portion of duodenum. Multiple cystic lesions suspected as metastases were found in the liver segment 8.
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Fig. 2
Magnetic resonance images of the liver.
A mass with inhomogenous enhancement abutted on the second portion of duodenum. Multiple cystic lesions in the liver showed low signal intensity after enhancement.
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Fig. 3
Gross finding of resected mesenteric mass.
A 5.5×5.3×5 cm sized round, slightly hard, well-circumscribed mass was shown here. The findings of hemorrage and necrosis were seen in the cut surface of the mass.
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Fig. 4
Microscopic findings of resected mesenteric mass
Hematoxylin and eosin stained section showed typical findings of neuroendocrine tumor (A: ×100, B: ×400). Imunohistochemical stain for synaptophysin was positive and that for S-100 was focal positive (C: ×400, D: ×400).
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Table 1
Clinical characteristics of the nine cases of mesenteric paraganglioma
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HCC, hepatocellular carcinoma; ND, not documented; M, months

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