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Kim, Koo, Lee, Kim, Cho, Lee, and Kim: A case of Paraganglioma Arising in the Transverse Mesocolon
Case Report
Journal of Korean Society of Endocrinology

Journal of Korean Society of Endocrinology 2005; 20(5): 496-501.

Published online: 20 May 2005

DOI: https://doi.org/10.3803/jkes.2005.20.5.496

A case of Paraganglioma Arising in the Transverse Mesocolon

Hong Il Kim, Bo Kyung Koo1, You Jin Lee1, Jin Taek Kim1, Young Min Cho1, Kuhn Uk Lee2, Seong Yeon Kim1

Department of internal medicine, Seoul National University College of Medicine, Korea.

1Department of Internal Medicine, Seoul National University College of Medicine, Korea.

2Department of Surgery, Seoul National University College of Medicine, Korea.

Received 8 August 2005       Accepted 23 August 2005

Copyright © 2005 Korean Endocrine Society

Abstract

Herein, a case of a solitary primary paraganglioma arising in the mesentery, found in a hypertensive 70-year-old woman, who presented with nausea and postprandial abdominal discomfort, is reported. Ultrasonography and computed tomography showed a hypervascular mass abutting the second portion of the duodenum. An exploratory laparotomy revealed a 5.5×5.3×5 cm sized mass in the mesentery of the transverse colon, which was histologically proven to be a paraganglioma. No intraoperative hemodynamic changes developed, and the postoperative course was uneventful. To our knowledge, this is the first case of a paraganglioma arising in the mesentery reported in Korea. Considering the unusual locations and the associated operative risk, it is necessary to rule out the possibility of a functioning paraganglioma in the preoperative differential diagnosis of an abdominal mass.

Keywords: paraganglioma, mesentery, transverse colon, abdominal mass

Figures and Tables

Fig. 1
Computed tomography of abdomen.
A 4~5 cm sized, well-enhanced hypervascular mass was detected around the second portion of duodenum. Multiple cystic lesions suspected as metastases were found in the liver segment 8.
jkse-20-496-g001
Fig. 2
Magnetic resonance images of the liver.
A mass with inhomogenous enhancement abutted on the second portion of duodenum. Multiple cystic lesions in the liver showed low signal intensity after enhancement.
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Fig. 3
Gross finding of resected mesenteric mass.
A 5.5×5.3×5 cm sized round, slightly hard, well-circumscribed mass was shown here. The findings of hemorrage and necrosis were seen in the cut surface of the mass.
jkse-20-496-g003
Fig. 4
Microscopic findings of resected mesenteric mass
Hematoxylin and eosin stained section showed typical findings of neuroendocrine tumor (A: ×100, B: ×400). Imunohistochemical stain for synaptophysin was positive and that for S-100 was focal positive (C: ×400, D: ×400).
jkse-20-496-g004
Table 1
Clinical characteristics of the nine cases of mesenteric paraganglioma
jkse-20-496-i001

HCC, hepatocellular carcinoma; ND, not documented; M, months

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