Postpartu depression is one of the most serious problems in maternal health because it affects not only the mother but also her family. Postpartum depression disturbs maternal-infant interaction and attachment. However, most postpartum depression patients ignore this problem and do not seek treatment. Thus this study in conducted to development of a Home-Based Multimedia Tutoring System for postpartum depression management. With this computerized system, mothers in the postpartum periods can check the level of postpartum depression using a personal computer. This system will go through each mother's data and screen those who have abnormal values. In addition this system includes intervention programs-education for nutrition, hygiene care, sleep, postpartum exercise, methods of relaxation, deep breathing, visualization, music therapy and family therapy-to relieve postpartum depression. Using this system, a mother who has a minor level of depression can manage it by herself. Computer language used in this study were html 3.2 OS used was Microsoftware Ni Server 4.0, the graphic tool was Adobe Photoshop 4.0, and the Webpage tool was Notepade. The results of this study are show at internet "URL : Http://203.241.225.42/". Finally, the author suggests that this system could be adequately applied to assessing postpartum depression and as a intervention strategy for mothers during the postpartum period. Further this study contributes to designing an appropriate postpartum depression prevention strategy.