Journal List > J Korean Diabetes Assoc > v.31(2) > 1062426

Lim, Park, Kim, and Cho: Waist Circumference May be More Important than Body Mass Index (BMI) in Determinants of Left Ventricular Mass in Korean Hypertensive Patients

Abstract

Background

In many studies, obesity is highly correlated with adverse coronary risk profile. Increased left ventricular (LV) mass is an independent risk factor for cardiovascular mortality and morbidity. Hypertension is an well known factor related with LV mass. Obesity also is related with LV mass and commonly associated with hypertension. However, few data are available concerning the relations of LV mass to central obesity, especially in Korean hypertensive patients. So, this study was to evaluate the significance of waist circumference in determinants of LV mass in Korean hypertensive patients.

Methods

A total of 74 hypertensive [40 women, 34 men; mean age, 62.5 years; mean body mass index (BMI), 25.0 kg/m2, 17 with type 2 diabetes] patients without prevalent cardiovascular disease were studied. Echocardiographic LV septal thickness, LV posterior wall thickness, LV dimension and LV mass were analysed.

Results

LV mass, diastolic left ventricular internal dimension and epicardial fat thickness were larger in men than in female. LV mass was larger in obese patients defined by body mass index and also in central obese patients defined by waist circumference. LV mass was correlated with sex, body mass index, waist circumference, diastolic left ventricular internal dimension, left ventricular posterior wall thickness and interventricular septal thickness. After controlling for age, sex and body mass index, waist circumference was correlated with LV posterior wall thickness and LV mass.

Conclusion

Waist circumference may be more important than BMI in determinants of left ventricular mass in Korean hypertensive patients.

Figures and Tables

Fig. 1
Left ventricular mass in normal (BMI < 23 kg/m2) and obese (BMI > 25 kg/m2) hypertensive patients.
jkda-31-130-g001
Fig. 2
Comparison of left ventricular mass between non-central obese and central obese hypertensive patients.
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Table 1
Characteristics of subjects
jkda-31-130-i001

LVDd, left ventricular diastolic internal dimension; LVPWd, diastolic left ventricular posterior wall thickness; IVSd, diastolic interventricular septal thickness; LV mass, left ventricular mass.

*P < 0.05.

Table 2
Pearson's correlation coefficiency of left ventricular mass
jkda-31-130-i002

LVDd, left ventricular diastolic internal dimension; LVPWd, diastolic left ventricular posterior wall thickness; IVSd, diastolic interventricular septal thickness; LV mass, left ventricular mass.

*P < 0.05.

Table 3
Partial correlation coefficiency of waist circumference after controlling for age, sex and body mass index
jkda-31-130-i003

LVDd, left ventricular diastolic internal dimension; LVPWd, diastolic left ventricular posterior wall thickness; IVSd, diastolic interventricular septal thickness; LV mass, left ventricular mass.

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