Journal List > J Korean Diabetes Assoc > v.30(2) > 1062369

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Jang, Kim, and Lee: A Case of Chronic Inflammatory Demyelinating Polyneuropathy in a Girl with Type 1 DM
Case Report
The Journal of Korean Diabetes Association

The Journal of Korean Diabetes Association 2006; 30(2): 130-135.

Published online: 31 March 2006

DOI: https://doi.org/10.4093/jkda.2006.30.2.130

A Case of Chronic Inflammatory Demyelinating Polyneuropathy in a Girl with Type 1 DM

Yi-Sun Jang, Hye-Soo Kim, Jong-Min Lee

Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Korea.

Received 15 November 2005       Accepted 6 January 2006

Copyright © 2006 Korean Diabetes Association

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an immune-mediated disorder characterized by the symmetrical weakness in both proximal and distal muscles for at least 2 months, hyporeflexia or areflexia, nerve conduction abnormalities, and high CSF protein level. Diabetes mellitus, monoclonal gammopathy, hepatitis C infection, HIV infection, SLE, Sjogren syndrome and lymphoma have been associated with CIDP. The incidence of CIDP in diabetes is not known exactly, but occur more common among diabetic than nondiabetic patients. There is sometimes a difficulty in distinguishing between diabetic polyneuropathy and CIDP, but differential diagnosis is important because CIDP is treatable with immune-modulating therapy.
We report a case of CIDP in 22-year-old girl with type 1 DM who presented with generalized motor weakness and walking disturbance which were treated with iv immunoglobulin.

Keywords: Chronic inflammatory demyelinating polyneuropathy, IV immunoglobulin, Type 1 DM

Figures and Tables

Fig. 1
General appearance of the patient. A: 2 years ago. before admission. B: At admission, she has weakness and atrophy of muscles in both extremities leading to walk disturbance.
jkda-30-130-g001
Fig. 2
Pes cavus deformity with hammer toe.
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Fig. 3
Diaphragmatic paralysis. There is little movement of the diaphragm between inspiration and expiration. A: full inspiration state. B: full expiration state.
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Table 1
Result of Nerve Conduction Study
jkda-30-130-i001

AbdPolBr: abductuor pollicis brevis, AbdDigMi: abductor digiti minimi, ExtDigiBr: extensor digitorum brevis, Tib Ant: Tibialis anterior B FH: below fibular head, A FH: above fibular head AbdHall: abductor hallucis.

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