Journal List > Korean J Endocr Surg > v.4(1) > 1060248

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Jung, Yoon, Nam, Chang, and Park: Thyroid Nodules in Patients with Secondary Hyperparathyroidism
Original Article

Korean Journal of Endocrine Surgery 2004; 4(1): 48-50.

Published online: 30 June 2004

DOI: https://doi.org/10.16956/kjes.2004.4.1.48

Thyroid Nodules in Patients with Secondary Hyperparathyroidism

Eun-Joo Jung, M.D., Jong Ho Yoon, M.D.1, Kee Hyun Nam, M.D., Hang-Seok Chang, M.D., Cheong Soo Park, M.D.

Department of Surgery, Yonsei University College of Medicine, Korea.

1Department of Surgery, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Korea.

Correspondence: ysurg@yumc.yonsei.ac.kr

      Accepted 23 September 2004

Copyright © 2004 Korean Association of Thyroid and Endocrine Surgeons; KATES

(open-access):

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

An association between primary hyperparathyroidism and well differentiated thyroid carcinoma has been frequently reported. However, there have been few reports of secondary hyperparathyroidism associated with thyroid carcinoma. This study was performed to evaluate the prevalence of thyroid nodule including thyroid carcinoma in patients with secondary hyperparathyroidism and to suggest more proper diagnostic approach for such cases.

Methods

A retrospective study was performed on fifty-two patients who underwent parathyroid surgery for secondary hyperparathyroidism between March, 1986 and December, 2003.

Results

In 20 patients (38.5%), thyroid surgery was added because of coexistent thyroid nodules. Five (25%) out of the 22 patients with coexistent thyroid nodule had thyroid carcinoma. Among the 5 thyroid carcinoma patients, 4 had papillary carcinomas and one had a follicular carcinoma. Mean size of thyroid carcinomas was 1.4 cm (0.3~3.0 cm).

Conclusion

The prevalence of thyroid carcinoma in patients with secondary hyperparathyroidism was higher than that in the general population. An aggressive diagnostic approach (ultrasonography and FNAB) should be considered when the patients with secondary hyperparathyroidism present with thyroid nodules.

Keywords: Secondary hyperparathyroidism, Thyroid Nodule, Thyroid Carcinoma

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