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Abstract
for PTC in selected cases. (Korean J Endocrine Surg Purpose: The aim of this study was to evaluate the operative feasibility and safety of endoscopic thyroidectomy via bilateral axillo breast approach (BABA) compared to conventional thyroidectomy in papillary thyroid carcinoma (PTC) patients.
Methods:
From July 2009 to November 2010, patients underwent BABA endoscopic thyroidectomy (ET group; n=41) or conventional open thyroidectomy (OT group; n=61) for PTC. Clinical and pathologic characteristics of patients, operation time, post-operative complications, cosmetic satisfaction and thyroglobulin (TG) level were analyzed retrospectively.
Results:
The mean age of the patients was 40.05±9.58 years (range 25∼61 years) and 46.21±13.68 years (range 19∼79 years) for the ET and OT group, respectively. The operative extent in the ET group did not include advanced thyroid cancer or lateral neck dissection. The size of the tumor was 0.78±0.59 cm (range 0.1∼3.00 cm) and 1.54 ±1.05 cm (range 0.3∼6.00 cm) for the ET and OT group, respectively. Extrathyroidal extension and number of retrieved lymph nodes were significantly higher in the OT group. Postoperative radioactive iodine ablation was performed on 25 patients (72.43%) in the ET group and 48 patients (78.69%) in the OT group. There was no abnormal uptake on radioactive iodine scans in the iodine-treated patients and no significant differences in postoperative off-T4 TG levels between the two groups. There were no significant differences in operative time, amount of drainage, postoperative hospitalization period, hypocalcemia, and vocal cord palsy between the two groups. Cosmetic results of ET group were rated as excellent in a 3-month postoperative questionnaire by 25 (72.43%) of 35 patients.
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Table 1.
Clinical characteristics of the patients in the two group
Table 2.
Pathologic characteristics and and the results of postoperative RAI ablation of the patients in the two group
| Total | Endoscopic group (n=41) | Open group (n=61) | P value |
|---|---|---|---|
| Tumor size (cm) | 0.78±0.59 (0.1∼3.00) | 1.54±1.05 (0.3∼6.00) | ＜0.01 |
| Extrathyroidal extension | 11/41 (26.83%) | 35/61 (57.38%) | ＜0.01 |
| Retrieved lymph node | 5.90±5.64 (1∼20) | 28.48±23.71 (1∼95) | ＜0.01 |
| [18.91±20.09 (1∼91)]∗ | ＜0.01 | ||
| Central LN metastasis | 5/41 (12.20%) | 37/61 (60.66%) | ＜0.01 |
| Lateral LN metastasis | 0/41 (0.00%) | 20/61 (32.79%) | ＜0.01 |
| Off T4-TG levels† | 0.71±1.69 (0∼8.25) | 1.90±5.73 (0∼41.20) | 0.20 |
| Tg ＜1.0 (ng/mL)† | 18/25 (72.00%) | 31/48 (64.58%) | 0.31 |
Table 3.
Comparison of postoperative complication between the two group
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