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Abstract
Purpose:
Ultrasound is most effective study for evaluating thyroid nodules. In this review, we discuss that sonographic findings to differentiate benign from malignant nodules and suggest recommendations for indications of fine needle aspiration biopsy and thyroid nodule management.
Methods:
Sonographic scans of 206 thyroid nodules in 164 patients were candidated for this study. We evaluated sonographic findings by shape, calcification, margin, and echogenicity, retrospectively. Sonographic findings that suggested malignancy included microcalcifications, a speculated margin, marked hypoechogenicity and a shape that was taller than wide. The final diagnosis of lesion as benign (n=180) or malignant (n=26) was confirmed by fine needle aspiration biopsy and follow-up (＞6 months). We demonstrated the difference of the sensitivity, specificity, positive predictive value, negative predictive value and accuracy.
Results:
Of 206 thyroid nodules, 26 were malignant. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy based on our sonographic classification method were 84.6%, 73.9%, 31.9%, 97.0% and 75.2%. Conclusion: Sonography can be helpful for making the differentiation between and malignant nodules. So, when well trained surgeon find thyroid nodules on sonography, we can make correct diagnosis of malignant nodules. (Korean J Endocrine Surg 2010;10:224-228)
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Table 1.
Ultrasonographic criteria for thyroid nodules
Table 2.
Comparison of sonographic and histologic findings
| Sonographic classification | Histologic finding | ||
|---|---|---|---|
| Malignant nodules (No) | Benign nodules (No) | Total (No) | |
| Malignant (No) | 22 | 47 | 69 |
| Benign (No) | 4 | 133 | 137 |
| Total (No) | 26 | 180 | 206 |
Table 3.
Sonographic findings in 206 malignant or benign nodules
Table 4.
Diagnostic index for individual sonographic criteria of malignant thyroid nodules
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