Journal List > J Lipid Atheroscler > v.4(2) > 1059551

Kang, Yeo, Lee, Yoon, Jo, Kim, and Lee: New Diagnostic Criterion of Ankle Brachial Index for Peripheral Arterial Disease

Abstract

Background

The ankle brachial index (ABI) is a simple, inexpensive diagnostic test for peripheral arterial disease (PAD). However the diagnostic criterion of 0.9 has shown variable accuracy for identification of stenosis. We investigated more specific and sensitive diagnostic criterion of ABI for the diagnosis of PAD.

Methods

Among 5,379 patients who performed ABI test, 398 patients with abnormal ABI results or PAD symptoms underwent computed tomography angiography to confirm PAD. Each ABI results were compared with its sensitivity, specificity, positive and negative predictive values. ROC analysis and cross-tabulation analysis were performed to yield proper ABI criterion.

Results

ABI of 0.9 showed very high level of sensitivity (92.2%) and very low specificity(59.3%). ABI of 0.84 showed high level of specificity (81.4%), sensitivity (82.2%) and diagnostic correspondent rate (0.607).

Conclusion

The ABI of 0.84 could be more accurate and useful diagnostic Criterion for identifying PAD.

Figures and Tables

Fig. 1
Receiver Operating Characteristic (ROC) curves for ABI for diagnosing peripheral vascular disease. The cutoff value of ABI was 0.84
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Table 1
Characteristics of the patients
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Mean±Standard deviation.

*p<0.001 PAD versus Non PAD

PAD; peripheral arterial disease, BMI (kg/m2); body mass index

Table 2
Sensitivity, Specificity, Positive predictive value, Negative predictive value, Diagnostic Correspondent Rate of ABI 0.8 to 0.9
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