Dyslipidemia in Older Adults and Management of Dyslipidemia in Older Patients

Kwang-il Kim

doi:10.12997/jla.2015.4.1.1

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Kim: Dyslipidemia in Older Adults and Management of Dyslipidemia in Older Patients

Review

Journal of Lipid and Atherosclerosis 2015; 4(1): 1-6.

Published online: 30 June 2015

DOI: https://doi.org/10.12997/jla.2015.4.1.1

Dyslipidemia in Older Adults and Management of Dyslipidemia in Older Patients

Kwang-il Kim

Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

Corresponding Author: Kwang-il Kim Kim, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Gumi-ro 166, Bundang-gu, Seongnam-si, Kyeongi-do 463-707, Korea. Tel: +82-31-787-7032, Fax: +82-31-787-4052, kikim907@snu.ac.kr

Received 19 May 2015 Revised 29 May 2015 Accepted 1 June 2015

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

In Korea, the number of older adults, particularly of the very elderly people, is expected to be increasing for the upcoming years. This demographic change has profound implication for medical and health care systems. As more people live a longer life, it is important to understand the chronic diseases or health problems which affect the health status or quality of life among the older adults. It has been well established that cardio-cerebrovascular diseases have important roles and impacts on functional capacity and health status of older adults. Recently, many risk factors which increase the risk of cardio-cerebrovascular diseases have been identified. Among them, dyslipidemia is one of the most important risk factor for cardio-cerebrovascular disease. However, there remain several questions regarding the clinical importance of dyslipidemia in older adults, safety and efficacy issue in treating dyslipidemia with statin in older adults, and the relationship between genetic factors associated with lipid profile and longevity. In this review, I will discuss current evidence and data on the topic of dyslipidemia in older adults.

Keywords: Dyslipidemia, Older adults, Cardiovascular disease, Statin

Figures and Tables

Fig. 1

Distribution of total cholesterol in Korean adults for age, sex, and menopausal status

Fig. 2

Comparison of relative (rel) and absolute (abs) risk reduction with statin therapy between patients aged <65 years and patients aged ≥65 years

Table 1

Genetic variation modulate HDL metabolism and longevity

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