Acute urticaria with angioedema following sea hare ingestion

Jin-Soo Park; Ji-Hye Kim; Moon-Gyung Yoon; Jung-Eun Kim; Yoo Seob Shin

doi:10.4168/aard.2016.4.1.61

Journal List > Allergy Asthma Respir Dis > v.4(1) > 1059232

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Park, Kim, Yoon, Kim, and Shin: Acute urticaria with angioedema following sea hare ingestion

Case Report

Allergy, Asthma & Respiratory Disease 2016; 4(1): 61-64.

Published online: 29 January 2016

DOI: https://doi.org/10.4168/aard.2016.4.1.61

Acute urticaria with angioedema following sea hare ingestion

Jin-Soo Park, Ji-Hye Kim, Moon-Gyung Yoon, Jung-Eun Kim, Yoo Seob Shin

Department of Allergy and Clinical Immunology, Ajou Uiversity Hospital, Suwon, Korea.

Correspondence to: Yoo Seob Shin. Department of Allergy and Clinical Immunology, Ajou Uiversity Hospital, 164 World cup-ro, Yeongtong-gu, Suwon 16499, Korea. Tel: +82-31-219-5155, Fax: +82-31-219-5154, drsys93@naver.com

Received 28 July 2015 Revised 9 September 2015 Accepted 14 September 2015

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/).

Abstract

Seafood is one of the common causes of food allergies to adults. The sea hare Aplysia kurodai is a marine mollusk which belongs to invertebrate gastropod that has been consumed as a food in Korea. Cases of acute toxic hepatitis after ingestion of sea hares have been reported, but few cases of allergic reactions to sea hare have been reported in the literature. A 33-year-old man was referred to our Emergency Department due to urticaria and periorbital/perioral swelling after eating sea hares. Approximately 10 years ago, he experienced similar allergic reactions to it. Skin prick and intradermal tests showed strong positive responses to crude sea hare allergen extract. He was diagnosed with food allergy to sea hares. We herein report the first case of sea hare allergy after ingestion.

Keywords: Aplysia, Gastropoda, Seafood, Urticaria, Angioedema

Figures and Tables

Fig. 1

The results of skin prick test (A) and intradermal test (B) to each extract of mollusks show positive reactions to sea hare (A. kurodai, Aplysia kurodai). B. cornutus, Batillus cornutus; H. midae, Haliotis midae.

Table 1

Skin prick test and intradermal test results of multiple seafood allergens

Allergen	Skin prick test		Intradermal test
Allergen	Wheal (mm)	Erythema (mm)	Wheal (mm)	Erythema (mm)
Aplysia kurodai	2×2	4×4	8×7	50×45
Boiled A. kurodai	4×3	20×12	23×14	56×47
Batillus cornutus	0	0	7×7	45×37
Sea squirt	0	0	6×5	50×37
Haliotis midae	2×2	2×2	10×8	45×35
Histamine	4×4	20×18	-	-
Saline	0	0	0	0

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ORCID iDs: Yoo Seob Shin
https://orcid.org/http://orcid.org/0000-0002-9855-3185
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