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Jongwook Yu, Eun Suk Son, Joonhwan Kim, Hong Suk Park, Sojung Lee, Sang Min Lee, Jeong-Woong Park, Sang Pyo Lee
Abstract
Abalone is popular seafood in Asia; however, allergy to abalone was rarely reported. We report a case of anaphylaxis after consumption of abalone. A 24-year-old female visited an Emergency Department, complaining of cough, dyspnea, rhinorrhea, generalized urticaria, facial edema, and wheezing that had developed 1 hour after consumption of abalone. She was discharged when her symptoms subsided after antihistamine and dexamethasone were given. One month later, she was referred to our outpatient clinic. We performed skin prick tests, measurement of serum specific IgE antibody level, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) with IgE immunoblotting. Both skin prick and specific IgE antibody tests were positive for abalone crude extract. In SDS-PAGE with IgE immunoblotting, we identified possible antigens sized 55, 100, and 25 kDa, respectively. This is the first case of abalone-induced anaphylaxis in Korea.
Figures and Tables
Fig. 1
IgE reactivity of sera to abalone measured by enzyme-linked immunosorbent assay. Bla, blank control.
Fig. 2
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the abalone protein. Lane M, molecular mass marker; Lane rAE, raw abalone's epipodium; Lane rAI, raw abalone's intestines; Lane sAE, steamed abalone's epipodium; Lane sAI, steamed abalone's intestines (steamed).
Fig. 3
IgE immunoblotting of the abalone protein with sera of patients and healthy control. ABE, abalone's epipodium; ABI, abalone's intestines.
Table 1
The result of skin prick test for raw and streamed abalone
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