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Abstract
Perilla is an Asian grain that consumed for food ingredient, oil crops, medicinal materials through the process of roasting. A 49-year-old male has been roasting grains for 10 years, who met with shortness of breath during the roasting perilla seeds, but not in other situations. Serum total immunoglobulin E (IgE) level, serum eosinophil count and skin prick test didn't showed significant results. Methacholine bronchial provocation test was positive (PC20 0.31 mg/mL). Specific bronchial provocation test with inhaling smoke from roasting perilla seeds showed a dual asthmatic response. Measured peak expiratory flow rate on his work place showed the result of 37% decrease at the end of work and full recovery at 6 hours after the end of work. Skin prick test to row perilla showed positive response with late symptoms. We diagnosed that the patient had an occupational asthma caused by inhaling smoke from roasting perilla seeds with IgE mediated mechanism.
Figures and Tables
Fig. 1
The results of bronchoprovocation test to perilla seeds. FEV1, forced expiratory volume in 1 second; PEFR, peak expiratory flow rate.
Fig. 2
The measurements of peak expiratory flow rate (PEFR) during the roasting work in his working place.
Fig. 3
The results of intradermal test to perilla seeds. The test showed positive responses at 10, 20 mg/mL with raw perilla seeds while the test with roasting perilla seeds showed negative responses (raw perilla 10 mg/mL: wheel 9 mm×8 mm, flare 9 mm×13 mm; raw perilla 20 mg/mL: wheel 9 mm×8 mm, flare 9 mm×8 mm; histamine: wheel 9 mm×8 mm, flare 10 mm×10 mm).
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