Clinical characteristics and cause of bronchiectasis in children: review in a center

Eun Ha Hwang; Hye-Young Kim; Min Ryu; Seong Heon Kim; Seung Kook Son; Young Mi Kim; Hee Ju Park

doi:10.4168/aard.2013.1.4.383

Journal List > Allergy Asthma Respir Dis > v.1(4) > 1058989

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Hwang, Kim, Ryu, Kim, Son, Kim, and Park: Clinical characteristics and cause of bronchiectasis in children: review in a center

Original Article

Allergy, Asthma & Respiratory Disease 2013; 1(4): 383-387.

Published online: 31 December 2013

DOI: https://doi.org/10.4168/aard.2013.1.4.383

Clinical characteristics and cause of bronchiectasis in children: review in a center

Eun Ha Hwang, Hye-Young Kim, Min Ryu, Seong Heon Kim, Seung Kook Son, Young Mi Kim, Hee Ju Park

Department of Pediatrics, Pusan National University School of Medicine, Busan, Korea.

Correspondence to: Hye-Young Kim. Department of Pediatrics, Pusan National University School of Medicine, 49 Busandaehak-ro, Yangsan 626-870, Korea. Tel: +82-51-240-7298, Fax: +82-51-248-6205, pearlhy@naver.com

Received 2 July 2013 Revised 23 August 2013 Accepted 27 August 2013

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/).

Abstract

Purpose

The study for bronchiectasis in children is rare in Korea. The aim of this study was investigate the clinical characteristic and associated etiology in pediatric patients with bronchiectasis.

Methods

We studied 29 pediatirc patients with bronchiectasis from January 2008 to December 2012 at Pusan National University Hospital. The age, sex, clinical symptoms, signs, radiologic findings, associated etiologic factors, and clinical course were investigated retrospectively.

Results

The median age at the time of diagnosis of bronchiectasis was 8.7 years. Chronic coughing was the most common symptom. The associated etiologies were immunodeficiency (31.0%), respiratory infection (27.6%), bronchiolitis obliterans (13.8%), interstitial lung disease (10.3%). The median age at the time of diagnosis of bronchiectasis in immunodeficient patients was 8.3 years. Post infectious bronchiectasis and severe respiratory symptom tend to occur in younger children.

Conclusion

The risk factors of bronchiectasis in children are immunodeficiency and respiratory infection. Physicians should evaluate bronchiectasis in children with chronic cough.

Keywords: Bronchiectasis, Etiology, Children, Immunodeficiency, Infection

Figures and Tables

Table 1

Investigation results

PCR, polymerase chain reaction.

Table 2

Clinical features and chest radiologic finding of patients with bronchiectasis

Table 3

Associated causes of bronchiectasis

SD, standard deviation.

Table 4

Lobar involvement of bronchiectasis

UL, upper lobe involvement; ML, middle lobe involvement; LL, lower lobe involvement.

^*Involvement of ≥4 lobes. ^†Involvement only on side. ^‡Involvement on both sides.

Notes

This study was supported by clinical investigation fund of Busan University Hospital.

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