Journal List > Korean J Neurotrauma > v.9(2) > 1058914

Cho, Park, Yun, and Moon: Comparative Analysis between Male and Female Osteoporotic Compression Fractures in Elderly Patients

Abstract

Objective

Osteoporosis results in increased fragility of the bone and thereby predisposes the patients to have a fracture with relatively little trauma. Osteoporosis is more common in women, however, its incidence in men is also increasing. Purpose of this article is to assess the clinical difference between male and female patient, and the effects of vertebroplasty or kyphoplasty.

Methods

Between January 2009 and December 2012, total 198 patients have undergone vertebroplasty or kyphoplasty for osteoporotic vertebral compression fractures and we selected 54 patients (27 male and 27 female) in this retrospective study. We investigated the difference of clinical characteristics between male and female osteoporotic vertebral compression fractures.

Results

There were no significant differences between the 2 groups in terms of distribution of body mass index, diabetes mellitus, hypertension, stroke, previous vertebroplasty or kyphoplasty. However, bone mineral density and vertebral compression fracture induced by trauma were significantly higher in male group. And preoperative visual analogue scale (VAS) is higher in male group.

Conclusion

Osteoporotic vertebral compression fracture induced by trauma is more frequent in men. Higher VAS score before operation in men might reflect this difference in etiology. The VAS scores decreased after operation in both men and women, suggesting vertebroplasty or kyphoplasty is effective in osteoporotic compression fracture regardless of etiology.

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TABLE 1.
Demographic and clinical characteristics
Characteristics Male (n=27) Female (n=27) p-value
Mean age 74.1±5.8 75.7±5.8 0.705
BMI 22.0±2.7 23.3±3.2 0.458
BMD –3.0±0.4 –3.3±0.4 0.004
Trauma history     0.004
 Yes (%) 23 (85.2) 13 (62.9)  
 No (%) 04 (14.8) 14 (38.1)  
Number of compression fracture     1.000
 Single (%) 23 (85.2) 23 (85.2)  
 Multiple (%) 04 (14.8) 04 (14.8)  
Underlying disease      
 Hypertension (%) 19 (70.4) 13 (48.1) 0.166
 DM (%) 03 (11.1) 04 (14.8) 0.665
 Stroke (%) 07 (25.9) 03 (11.1) 0.161
 Previous vertebroplasty or kyphoplasty history (%) 10 (37.0) 07 (25.9) 0.379

BMI: body mass index, BMD: bone mineral density, DM: diabetes mellitus

TABLE 2.
Change of Visual Analogue Scale (VAS) after operation
Preoperative score Postoperative score p-value
1 week post-op 3 months post-op
Male 7.2±1.3 3.3±0.6 2.3±0.7 <0.001
Female 6.2±0.7 3.0±0.7 2.3±0.5 <0.001
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