Journal List > Ewha Med J > v.37(2) > 1058592

TOOLS
Lee, Son, Lee, and Choi: Acute Bacterial Meningitis Caused by Neisseria cinerea
Case Report

The Ewha Medical Journal 2014; 37(2): 109-111.

Published online: 30 September 2014

DOI: https://doi.org/10.12771/emj.2014.37.2.109

Acute Bacterial Meningitis Caused by Neisseria cinerea

Ko Eun Lee, Hyo Moon Son, Miae Lee1, Hee Jung Choi

Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.

1Department of Laboratory Medicine, Ewha Womans University School of Medicine, Seoul, Korea.

Corresponding author: Hee Jung Choi. Department of Internal Medicine, Ewha Womans University School of Medicine, 1071 Anyangcheon-ro, Yangcheon-gu, Seoul 158-710, Korea. Tel: 82-2-2650-6008, Fax: 82-2-2655-2076, heechoi@ewha.ac.kr

Received 23 November 2013       Accepted 8 April 2014

Copyright © 2014. Ewha Womans University School of Medicine

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Neisseria cinerea is an oropharyngeal normal flora known as a non-pathogenic gram-negative diplococcus. Encephalo-meningitis related to N. cinerea is very rare. A 15-year-old healthy male visited emergency room for altered mentality with fever, headache, and vomiting. Physical examination showed abdominal tenderness and neck stiffness but there was no skin rash. Cerebrospinal fluid (CSF) examination revealed opening pressure of 210 mmH2O, red blood cell 200/mm3, white blood cell 8,320/mm3, neutrophil 84%, glucose 34 mg/dL, suggesting acute bacterial meningitis. Empirical antibiotics were administered and N. cinerea was identified in CSF culture. The patient showed complete recovery 10 days after administration of ceftriaxone. We report this case as the first N. cinerea meningitis in Korea.

Keywords: Neisseria cinerea, Meningitis

References

1. Knapp JS, Hook EW 3rd. Prevalence and persistence of Neisseria cinerea and other Neisseria spp. in adults. J Clin Microbiol. 1988; 26:896–900.
2. Kirchgesner V, Plesiat P, Dupont MJ, Estavoyer JM, Guibourdenche M, Riou JY, et al. Meningitis and septicemia due to Neisseria cinerea. Clin Infect Dis. 1995; 21:1351.
3. Boyce JM, Taylor MR, Mitchell EB Jr, Knapp JS. Nosocomial pneumonia caused by a glucose-metabolizing strain of Neisseria cinerea. J Clin Microbiol. 1985; 21:1–3.
4. Dossett JH, Appelbaum PC, Knapp JS, Totten PA. Proctitis associated with Neisseria cinerea misidentified as Neisseria gonorrhoeae in a child. J Clin Microbiol. 1985; 21:575–577.
5. Clausen CR, Knapp JS, Totten PA. Lymphadenitis due to Neisseria cinerea. Lancet. 1984; 1:908.
6. van de Beek D, de Gans J, Tunkel AR, Wijdicks EF. Community-acquired bacterial meningitis in adults. N Engl J Med. 2006; 354:44–53.
7. van de Beek D, de Gans J, Spanjaard L, Weisfelt M, Reitsma JB, Vermeulen M. Clinical features and prognostic factors in adults with bacterial meningitis. N Engl J Med. 2004; 351:1849–1859.
8. Schuchat A, Robinson K, Wenger JD, Harrison LH, Farley M, Reingold AL, et al. Bacterial meningitis in the United States in 1995. N Engl J Med. 1997; 337:970–976.
9. Lee JH, Cho HK, Kim KH, Kim CH, Kim DS, Kim KN, et al. Etiology of invasive bacterial infections in immunocompetent children in Korea (1996-2005): a retrospective multicenter study. J Korean Med Sci. 2011; 26:174–183.
10. Scarborough M, Thwaites GE. The diagnosis and management of acute bacterial meningitis in resource-poor settings. Lancet Neurol. 2008; 7:637–648.
11. Kim HS, Heo ST, Bae IG, Lim MH, Kim JH, Yun SE, et al. A case of acute bacterial meningitis caused by Vibrio vulnificus. Korean J Med. 2010; 78:523–526.
12. van Crevel H, Hijdra A, de Gans J. Lumbar puncture and the risk of herniation: when should we first perform CT? J Neurol. 2002; 249:129–137.
13. Hasbun R, Abrahams J, Jekel J, Quagliarello VJ. Computed tomography of the head before lumbar puncture in adults with suspected meningitis. N Engl J Med. 2001; 345:1727–1733.
14. Coureuil M, Join-Lambert O, Lecuyer H, Bourdoulous S, Marullo S, Nassif X. Mechanism of meningeal invasion by Neisseria meningitidis. Virulence. 2012; 3:164–172.
15. Sigurdardottir B, Bjornsson OM, Jonsdottir KE, Erlendsdottir H, Gudmundsson S. Acute bacterial meningitis in adults: a 20-year overview. Arch Intern Med. 1997; 157:425–430.
TOOLS
Similar articles