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Chang, Chung, Yoon, Kim, and Choi: Two Cases of Dengue Fever Due to Dengue Virus-1 Developed in a Family
Case Report

The Ewha Medical Journal 2013; 36(Suppl): S1-S4.

Published online: 23 December 2013

DOI: https://doi.org/10.12771/emj.2013.36.S.S1

Two Cases of Dengue Fever Due to Dengue Virus-1 Developed in a Family

Ji Young Chang, Un Kyo Chung, Seo Hee Yoon1, Kyung-Hyo Kim1, Hee Jung Choi

Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.

1Department of Pediatrics, Ewha Womans University School of Medicine, Seoul, Korea.

Corresponding author: Hee Jung Choi. Department of Internal Medicine, Ewha Womans University School of Medicine, 1071 Anyangcheon-ro, Yangcheon-gu, Seoul 158-710, Korea. Tel: 82-2-2650-6008, Fax: 82-2-2655-2076, heechoi@ewha.ac.kr

Received 7 June 2013       Accepted 20 November 2013

Copyright © 2013. Ewha Womans University School of Medicine

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We report two cases of dengue fever due to DENV-1 in the family members who returned from Manila, Philippines. Case 1: A 41-year-old female visited the clinic with a general weakness. She had a fever for 5 days. When she came back to Korea, her fever had subsided. The immunoglobulin M (IgM)-capture enzyme-linked immunosorbent assay for dengue virus was positive. Case 2: A 11-year-old female was admitted to the pediatric department after reporting symptoms of fever and abdominal pain upon returning from the Philippines. The RT-PCR result for DENV-1 was positive in blood, but IgM came out negative. Dengue fever should be suspected for those who have returned from an endemic area with reports of febrile illness and rash, particularly if thrombocytopenia, leukopenia, elevated serum aminotransferase are present. Using RT-PCR and serological test, the precise diagnosis should be made and proper management should be given to prevent secondary complications.

Keywords: Clinical manifestation, Dengue fever, Dengue virus serotype, Diagnosis

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