Journal List > Ewha Med J > v.36(2) > 1058581

Kim and Kim: Treatment of Obstructive Sleep Apnea with Oral Appliance

Abstract

Oral appliances have been considered as effective treatment modality for obstructive sleep apnea (OSA). Especially mandibular advanced device (MAD) showed more effective treatment results compared to other oral appliances. With the accurate diagnosis through polysomnography, clinical examination and radiographic examination, the appropriate application of oral appliances would show promising results for OSA and snoring. However oral appliances can raise the complications such as untoward movement of teeth and development of temporomandibular joint disorders, thus it is highly recommended that the treatment Should be undertaken by skilled dental specialists. Moreover, periodic check-up and adjustment of appliances, if needed, should be performed. Although the assertion that continuous positive airway pressure is superior to MAD physiologically, consensus is not available until now. For optimum treatment for OSA, further researches are necessary for investigation of long-term efficiency, performance, cardiovascular status and objective adaptation.

Figures and Tables

Table 1
Representative studies presenting the treatment outcomes of MAD and CPAP*
emj-36-97-i001

MRA, mandibular repositioning appliance; CPAP, continuous positive airway pressure; RDI, respiratory disturbance index (event per hour); PCS, propective case series; RCT, randomized controlled trial; NG, not given; NA, not applicable. *Values are presented as mean±standard error of the mean, unless so marked, all other values are mean±standard deviation. P<0.05 compared with baseline. P<0.05 compared with MRA. Adapted from Mohsenin et al. [26] with permission from ADA Publishing Co.

Table 2
Protocol for treatment with oral appliance.
emj-36-97-i002

References

1. Guilleminault C, Tilkian A, Dement WC. The sleep apnea syndromes. Annu Rev Med. 1976; 27:465–484.
2. Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med. 2002; 165:1217–1239.
3. Olson LG, King MT, Hensley MJ, Saunders NA. A community study of snoring and sleep-disordered breathing. Health outcomes. Am J Respir Crit Care Med. 1995; 152:717–720.
4. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research: the Report of an American Academy of Sleep Medicine Task Force. Sleep. 1999; 22:667–689.
5. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993; 328:1230–1235.
6. Young T, Evans L, Finn L, Palta M. Estimation of the clinically diagnosed proportion of sleep apnea syndrome in middle-aged men and women. Sleep. 1997; 20:705–706.
7. Sher AE, Schechtman KB, Piccirillo JF. The efficacy of surgical modifications of the upper airway in adults with obstructive sleep apnea syndrome. Sleep. 1996; 19:156–177.
8. Janson C, Gislason T, Bengtsson H, Eriksson G, Lindberg E, Lindholm CE, et al. Long-term follow-up of patients with obstructive sleep apnea treated with uvulopalatopharyngoplasty. Arch Otolaryngol Head Neck Surg. 1997; 123:257–262.
9. Brown DJ, Kerr P, Kryger M. Radiofrequency tissue reduction of the palate in patients with moderate sleep-disordered breathing. J Otolaryngol. 2001; 30:193–198.
10. Practice parameters for the use of laser-assisted uvulopalatoplasty: Standards of Practice Committee of the American Sleep Disorders Association. Sleep. 1994; 17:744–748.
11. Hoekema A, Stegenga B, De Bont LG. Efficacy and co-morbidity of oral appliances in the treatment of obstructive sleep apnea-hypopnea: a systematic review. Crit Rev Oral Biol Med. 2004; 15:137–155.
12. Lojander J, Maasilta P, Partinen M, Brander PE, Salmi T, Lehtonen H. Nasal-CPAP, surgery, and conservative management for treatment of obstructive sleep apnea syndrome: a randomized study. Chest. 1996; 110:114–119.
13. Jenkinson C, Davies RJ, Mullins R, Stradling JR. Comparison of therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised prospective parallel trial. Lancet. 1999; 353:2100–2105.
14. Song Y. Treatment of snoring and obstructive sleep apnea: oral appliance therapy of snoring and OSA. J Korean Dent Assoc. 2010; 48:190–195.
15. Lowe AA, Sjoholm TT, Ryan CF, Fleetham JA, Ferguson KA, Remmers JE. Treatment, airway and compliance effects of a titratable oral appliance. Sleep. 2000; 23:Suppl 4. S172–S178.
16. Menn SJ, Loube DI, Morgan TD, Mitler MM, Berger JS, Erman MK. The mandibular repositioning device: role in the treatment of obstructive sleep apnea. Sleep. 1996; 19:794–800.
17. Lindman R, Bondemark L. A review of oral devices in the treatment of habitual snoring and obstructive sleep apnoea. Swed Dent J. 2001; 25:39–51.
18. Schmidt-Nowara W, Lowe A, Wiegand L, Cartwright R, Perez-Guerra F, Menn S. Oral appliances for the treatment of snoring and obstructive sleep apnea: a review. Sleep. 1995; 18:501–510.
19. Cameron DA, Lyons MF, Fox DL, Banham SW. Pilot study of a semi-flexible intra-oral appliance for the control of snoring. Br Dent J. 1998; 185:304–307.
20. Arai H, Furuta H, Kosaka K, Kaneda R, Koshino Y, Sano J, et al. Changes in work performances in obstructive sleep apnea patients after dental appliance therapy. Psychiatry Clin Neurosci. 1998; 52:224–225.
21. Bloch KE, Iseli A, Zhang JN, Xie X, Kaplan V, Stoeckli PW, et al. A randomized, controlled crossover trial of two oral appliances for sleep apnea treatment. Am J Respir Crit Care Med. 2000; 162:246–251.
22. Marklund M, Franklin KA, Sahlin C, Lundgren R. The effect of a mandibular advancement device on apneas and sleep in patients with obstructive sleep apnea. Chest. 1998; 113:707–713.
23. Marklund M, Persson M, Franklin KA. Treatment success with a mandibular advancement device is related to supine-dependent sleep apnea. Chest. 1998; 114:1630–1635.
24. Tan YK, L'Estrange PR, Luo YM, Smith C, Grant HR, Simonds AK, et al. Mandibular advancement splints and continuous positive airway pressure in patients with obstructive sleep apnoea: a randomized cross-over trial. Eur J Orthod. 2002; 24:239–249.
25. Chan AS, Cistulli PA. Oral appliance treatment of obstructive sleep apnea: an update. Curr Opin Pulm Med. 2009; 15:591–596.
26. Mohsenin N, Mostofi MT, Mohsenin V. The role of oral appliances in treating obstructive sleep apnea. J Am Dent Assoc. 2003; 134:442–449.
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