A Case of Pulmonary Artery Endarteritis due to Staphylococcus lugdunensis in Patient with Clinically Silent Patent Ductus Arteriosus

Mahn Lee; Hyun Jung Song; Jeong-A Lee

doi:10.12771/emj.2011.34.2.51

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Lee, Song, and Lee: A Case of Pulmonary Artery Endarteritis due to Staphylococcus lugdunensis in Patient with Clinically Silent Patent Ductus Arteriosus

Case Report

The Ewha Medical Journal

The Ewha Medical Journal 2011; 34(2): 51-54.

Published online: 30 September 2011

DOI: https://doi.org/10.12771/emj.2011.34.2.51

A Case of Pulmonary Artery Endarteritis due to Staphylococcus lugdunensis in Patient with Clinically Silent Patent Ductus Arteriosus

Mahn Lee, Hyun Jung Song, Jeong-A Lee¹

Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.

¹Department of Internal Medicine, Hallym University College of Medicine, Anyang, Korea.

Corresponding author (jalee@hallym.ac.kr)

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Staphylococcus lugdunensis (S. lugdunensis) is an unusually virulent coagulase-negative staphylococci (CNS) and uncommon cause of infective endocarditis (IE) involving mainly native left sided valves. S. lugdunensis IE, which was described previously as "surreptitious" and "wolf in sheep's clothing", runs an aggressive course with a high rate of severe in-hospital complications. Therefore, early surgical treatment has been considered for the treatment of S. lugdunensis IE. However, we experienced a case of S. lugdunensis pulmonary endarteritis which was cured with antibiotic therapy alone.

Keywords: Staphylococcus lugdunensis, Pulmonary endarteritis

Figures and Tables

Fig. 1

Transthorasic echocardiography finding. Patent ductus arteriosus communicated with descending aorta and Lt. pulmonary artery is noted.

Fig. 2

Transthorasic echocardiography finding. A 1.5×1.0 cm sized vegetation at left pulmonary artery is seen.

Fig. 3

Chest CT finding. Chest CT on hospital day 3 shows embolism in left pulmonary artery.

Fig. 4

Chest CT finding. One month later, embolism in left pulmonary artery is disappeared.

References

1. von Eiff C, Peters G, Heilmann C. Pathogenesis of infections due to coagulase-negative staphylococci. Lancet Infect Dis. 2002. 2:677–685.

2. Van Hoovels L, De Munter P, Colaert J, Surmont I, Van Wijngaerden E, Peetermans WE, et al. Three cases of destructive native valve endocarditis caused by Staphylococcus lugdunensis. Eur J Clin Microbiol Infect Dis. 2005. 24:149–152.

3. Anguera I, Del Río A, Miró JM, Matínez-Lacasa X, Marco F, Gumá JR, et al. Staphylococcus lugdunensis infective endocarditis: description of 10 cases and analysis of native valve, prosthetic valve, and pacemaker lead endocarditis clinical profiles. Heart. 2005. 91:e10.

4. Seenivasan MH, Yu VL. Staphylococcus lugdunensis endocarditis-the hidden peril of coagulase-negative staphylococcus in blood cultures. Eur J Clin Microbiol Infect Dis. 2003. 22:489–491.

5. Thilen U, Astrom-Olsson K. Does the risk of infective endarteritis justify routine patent ductus arteriosus closure? Eur Heart J. 1997. 18:503–506.

6. Choi KN, Yang TH, Park BS, Jun HJ, Um SJ, Seol SH, et al. Case with patent ductus arteriosus complicated by pulmonary artery endarteritis. J Cardiovasc Ultrasound. 2008. 16:90–92.

7. Choi SH, Park HG, Byun SW, Koo DH, Kang HS, Jang HJ, et al. A case of infective endocarditis due to Staphylococcus lugdunensis. Infect Chemother. 2006. 38:277–281.

8. Cho HJ, Seol SH, Park SY, Jun HS, Kim DK, Kim DI, et al. A case of native valve infective endocarditis caused by Staphylococcus lugdunensis. Korean J Med. 2011. 80:212–215.

9. Ha YE, Rye SY, Ko KS, Joo EJ, Park SY, Kim HA, et al. Native valve infective endocarditis due to Staphylococcus lugdunensis confirmed by 16S ribosomal RNA Sequencing. Infect Chemother. 2011. 43:372–376.

10. Frank KL, Del Pozo JL, Patel R. From clinical microbiology to infection pathogenesis: how daring to be different works for Staphylococcus lugdunensis. Clin Microbiol Rev. 2008. 21:111–133.

11. Ozkokeli M, Ates M, Uslu N, Akcar M. Pulmonary and aortic valve endocarditis in an adult patient with silent patent ductus arteriosus. Jpn Heart J. 2004. 45:1057–1061.

12. Sadiq M, Latif F, Ur-Rehman A. Analysis of infective endarteritis in patent ductus arteriosus. Am J Cardiol. 2004. 93:513–515.

13. Bain RC, Edwards JE, Scheifley CH, Geraci CE. Right sided bacterial endocarditis and endarteritis, clinical and pathological study. Am J Med. 1958. 24:98–110.

14. Schneider DJ, Moore JW. Patent ductus arteriosus. Circulation. 2006. 114:1873–1882.

15. Balzer DT, Spray TL, McMullin D, Cottingham W, Canter CE. Endarteritis associated with a clinically silent patent ductus arteriosus. Am Heart J. 1993. 125:1192–1193.

16. Radman FB, Beanlands DS, Burwash IG. Isolated pulmonic valve endocarditis in healthy hearts: a case report and review of the literature. Can J Cardiol. 2000. 16:1282–1289.

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