Journal List > Korean J Schizophr Res > v.15(1) > 1057777

Lee and Choi: Prevalence of the Metabolic Syndrome among Outpatients with Schizophrenia or Schizoaffective Disorder



The aim of this study were to assess a) the prevalence of metabolic syndrome in outpatients with schizophrenia or schizoaffective disorder, b) the comparison of characteristics of patients with or without the metabolic syndrome, c) the sensitivity, specificity and positive predictive values of individual criteria for metabolic syndrome.


This study assessed the prevalence of the metabolic syndrome among 128 schizophrenia or schizoaffective disorder patients using the National Cholesterol Education Program-Adult Treatment Panel III.


Of patients, 54.7% (M : 49.3%, F : 61.4%) had metabolic syndrome. The metabolic syndrome was associated with medical history of diabetes, hypertension and dyslipidemia. Presence of abdominal obesity was most sensitive (97.1%), while raised fasting glucose was most specific (89.7%). Combining abdominal obesity/raised triglycerides and abdominal obesity/low HDL cholesterol had 100% sensitivity.


The metabolic syndrome is highly prevalent among outpatients with schizophrenia or schizoaffective disorder. This study suggests that the measurement of abdominal obesity is a simple test to identify individuals at high risk for metabolic syndrome.

Figures and Tables

Table 1
Comparison of the characteristics of patients with or without the Metabolic syndrome

a : chi-square test, b : t-test, c : wilcoxon rank sum test

20 cases are missing in duration of illness, medical illness : diabetes or hypertension or dyslipidemia, exercise : ≥90 min/week, alcohol : ≥1 time/week, smoking : current smoker

Table 2
Predictive value of the individual criteria of the Metabolic syndrome

Sensitivity=correct prediction of cases ; specificity=correct prediction of non-cases ; positive predictive value=probability of a condition being present if the test is positive


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