Deficit of Executive Control of Positive Emotional Information and Its Association with Social Anhedonia in Schizophrenia

Jae-Sub Park; Ji-Won Chun; Il-Ho Park; Eo-Su Kim; Jae-Jin Kim

doi:10.0000/kjsr.2012.15.1.27

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Park, Chun, Park, Kim, and Kim: Deficit of Executive Control of Positive Emotional Information and Its Association with Social Anhedonia in Schizophrenia

Original Article

Korean Journal of Schizophrenia Research

Korean Journal of Schizophrenia Research 2012; 15(1): 27-33.

Published online: 30 June 2012

DOI: https://doi.org/10.0000/kjsr.2012.15.1.27

Deficit of Executive Control of Positive Emotional Information and Its Association with Social Anhedonia in Schizophrenia

Jae-Sub Park, MD¹, Ji-Won Chun, MD, PhD², Il-Ho Park, MD³, Eo-Su Kim, MD^1,², Jae-Jin Kim, MD^1,²

¹Department of Psychiatry, Yonsei University College of Medicine, Seoul, Korea.

²Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.

³Department of Psychiatry, Myongji Hospital, Kwandong University, Goyang, Korea.

Address for correspondence: Jae-Jin Kim, Department of Psychiatry, Yonsei University Gangnam Severance Hospital, 211 Eonju-ro, Gangnam-gu, Seoul 135-720, Korea. Tel: 02-2019-3341, Fax: 02-3462-4304, jaejkim@yonsei.ac.kr

Received 28 April 2012 Revised 20 May 2012 Accepted 22 May 2012

Abstract

Objectives

Schizophrenia has been considered to be characterized by an abnormality in attention, especially in the executive control. Emotion is an important component of the executive control. The aim of this study was to investigate the influence of emotion on the executive control in patients with schizophrenia.

Methods

Participants were 20 healthy controls and 19 subjects with schizophrenia. They viewed full-color pictures selected from the International Affective Picture System. During each trial, an emotional picture, which was either positive or negative, lit up on either the left or right side. Participants were instructed to respond to the emotional valance of each stimulus by pressing a button with their left or right index finger, while ignoring its presented side.

Results

There was a group difference in the response time, and patients with schizophrenia exhibited an impairment in the executive control of emotional information. However, there was no difference in the response time between the emotional conditions. In the patient group, the missing rate in the positive emotional condition was correlated with the severity of social anhedonia, whereas the missing rate in the negative emotional condition was correlated with the severity of positive symptoms.

Conclusion

Patients with schizophrenia have a deficit in the executive control of positive emotional information as well as negative emotion, but it may be due to different underlying mechanisms.

Keywords: Schizophrenia, Emotion, Conflict, Attention, Anhedonia

Figures and Tables

Fig. 1

Emotional discrimination task and four conditions, the positive congruent, negative congruent, positive incongruent and negative incongruent.

Fig. 2

Interaction among correct response rate, missing rate and response time in different conditions. ^*: statistically significant p<0.05.

Fig. 3

Pearson correlations of the missing rate with anhedonia scores and PANSS in patients with schizophrenia ^*: p<0.05, ^†: p<0.01. PANSS : Positive and Negative Syndrome Scale.

Table 1

Demographic and clinical profiles

Values are mean±SD. PANSS : Positive and Negative Syndrome Scale, RPM : Raven's progressive matrices

Table 2

Comparison of correct response rate, missing rate and response time between schizophrenia patients and normal controls

Values are mean±SD

Table 3

Pearson correlations between age and education, behavioral data, symptom scales in patients with schizophrenia

^*: statistically significant p<0.05, ^†: statistically significant p<0.01. PANSS : Positive and Negative Syndrome Scale, RPM : Raven's Progressive Matrices

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