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Shin, Kim, Cho, Choi, and Song: Relationship between cancer and oral health in Korean adults determined using data from the 6th (2013-2014) Korea National Health and Nutritional Examination Survey
Original Article

Journal of Korean Academy of Oral Health 2017; 41(1): 16-21.

Published online: 31 March 2017

DOI: https://doi.org/10.11149/jkaoh.2017.41.1.16

Relationship between cancer and oral health in Korean adults determined using data from the 6th (2013-2014) Korea National Health and Nutritional Examination Survey

Hae-Eun Shin1, Hyun-Jin Kim2, Min-Jeong Cho1, Youn-Hee Choi1, Keun-Bae Song1

1Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea.

2Department of Dental Science, Graduate School, Kyungpook National University, Daegu, Korea.

Corresponding Author: Keun-Bae Song. Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, 2177 Dalgubeol-daero, Junggu, Daegu 41940, Korea. Tel: +82-53-660-6875, Fax: +82-53-423-2947, kbsong@knu.ac.kr

Received 5 December 2016       Revised 8 February 2017       Accepted 24 February 2017

Copyright © 2017 by Journal of Korean Academy of Oral Health

(open-access):

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives

Dental caries and periodontitis are major oral bacterial infections associated with dental plaque. Infection and inflammation play a role in carcinogenesis, and a significant link has been found between some highly prevalent oral and dental diseases and some types of cancer. Therefore, the aim of this study was to evaluate the relationship between cancer and oral health among Korean adults.

Methods

Data from the 6th Korea National Health and Nutrition Examination Survey were used to analyze the incidence of cancer according to oral health. Demographic and socioeconomic statuses and oral behavior of the participants was analyzed using complex chi-square tests. Logistic regression was used to analyze the relationship between a high DMFT index and cancer by calculating the 95% confidence intervals.

Results

In total, 6,450 case-control subjects were included. Significant difference was observed in the DMFT index, but not in periodontal diseases, between the cases and controls. The odds ratio for cancer was 1.80 (95% confidence interval: 1.18 to 2.73) in the high-risk group. However, no significant difference was observed after adjusting for age, education level, and income.

Conclusions

The results provide potential evidence of a significant association between cancer and oral disease.

Keywords: Cancer, DMFT index, Korea National Health and Nutrition Examination Survey (KNHANES), Oral health

Figures and Tables

Table 1

Demographic distribution according to cancer N (%)

jkaoh-41-16-i001

BMI, body mass index.

The data were analysed by complex samples.

*Chi-square test.

Table 2

Oral health behavior and cancer N (%)

jkaoh-41-16-i002

The data were analysed by complex samples.

*Chi-square test.

Table 3

Distribution of periodontitis according to cancer classification N (%)

jkaoh-41-16-i003

The data were analysed by complex samples.

*Chi-square test.

Table 4

DMFT index according to cancer classification (mean±SD)

jkaoh-41-16-i004

The data were analysed by complex samples.

*Generalized linear model.

Table 5

Relationship between high DMFT index and cancer

jkaoh-41-16-i005

OR, odds ratio; CI, 95% confidence intervals.

The data were analysed by complex samples.

*Logistic regression.

Model I: Unadjusted model, Model II: Age adjusted, Model III: Age, education and income adjusted.

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