Journal List > J Korean Acad Oral Health > v.38(4) > 1057612

Cho, Kim, and Shin: Drug prescription rates in dental health services

Abstract

Objectives

This study examined the misuse and abuse of antibiotics in relation to the demographic and socioeconomic characteristics of patients given prescriptions by dental providers.

Methods

We examined data collected in 2011 by the Korea Health Panel from 3,836 dental visits. The data included multiple visits per individual for 3,738 household members of 2,588 households using outpatient dental services. The data were analyzed by dental service provider type, using four types of -regression. Model analysis and comparison were performed using Akaike’s information criterion (AIC) and Bayesian information criterion (BIC) to select the best model.

Results

Prescription rates according to type of dental service provider are as follows: 18% by dental hospitals and 19%-20% by dental clinics. The patient factors contributing to the prescription rate are gender, age, education, and income level. Higher antibiotics exposure was found in patients who were male, older, with less education, and lower incomes. Patient exposure to antibiotics did not significantly differ between dental hospitals and dental clinics.

Conclusions

When prescribing antibiotics in dental practices, patient safety can be improved by reducing misuse and abuse of antibiotics through consideration of individual patient characteristics.

References

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Table 1.
Variables of the study subject
Independent variables Reference
Demographic Gender Male Male
Female
Age 20-40 years 20-40 years
≤19 years
40-65 years
≥65 years
Martial status Married Married
Divorced/Widowed/Separated
Unmarried
Socio-economic Education ≤Primary school ≤Primary school
Middle school
High school
≥College
Economic Activity Active
Activity Non-activity
Household income quartile Low Low
Low-middle
High-middle
High
Private Uninsured Uninsured
Health Fixed benefit insured
Insurance Indemnity insured
Health Chronic Yes Yes
Disease No
Table 2.
Handling of beta regression according to occurring 0's and 1's
Model Analytical methods Brief description
Model 1 Beta Ignore 0s and 1s
Model 2 +―0.005 or 0.01 Transform dependent variables to add a small amount using 0.005 or 0.01 to the lower
Model 3 ZOIB (zero one inflated beta) bound, and to subtract the same amount from the upper bound Consists of three parts : a logistic regression model for whether or not the proportion equals
0 and 1, a beta model for the proportions between 0 and 1 For situations where the decision for proportions of 0 and/or 1 are governed by a different
Model 4* y“=(y‘(N-1) + 0.5)/N process as the other proportions Compress the range to avoid zeros and ones by taking Smithson and Verkuilen propose the formula next to it

*Description of model 4 N=sample size.

Table 3.
Demographic characteristics of dental outpatients
Variables Classification Frequency %
Gender Male 1,687 43.98
Female 2,149 56.02
Age ≤19 years 1,127 29.38
20-40 years 654 17.05
40-65 years 1,366 35.61
≥65 years 689 17.96
Marital Status Married 2,050 53.44
Unmarried 1,460 38.06
Divorced/Widowed/Separated 326 8.50
Education ≤Primary school 1,358 35.40
Middle school 558 14.55
High school 1,004 26.17
≥College 916 23.88
Economic Activity Activity 2,266 59.07
Non-activity 1,570 40.93
Chronic Disease Yes 2,398 62.51
No 1,438 37.49
Household income Low 959 25.00
quartile Low-middle 960 25.03
High-middle 959 25.00
High 958 24.97
Private Health Uninsured 949 24.74
Insurance Fixed benefit insured 2,310 60.22
Indemnity insured 577 15.04
Table 4.
Mean of prescribing rates according to demographic characteristics of dental outpatients and the dental institutions
Variables Classification Model 1 Model 2 Model 4 P
mean±sd mean±sd mean±sd
Gender Male 0.21±0.34 0.21±0.33 0.21±0.34 0.002*
Female 0.18±0.32 0.18±0.31 0.18±0.32
Age ≤19 years 0.03±0.16a 0.04±0.15a 0.03±0.16a <0.001
20-40 years 0.18±0.32b 0.19±0.31b 0.18±0.32b
40-64 years 0.25±0.36c 0.25±0.35c 0.25±0.36c
≥65 years 0.34±0.38d 0.34±0.38d 0.34±0.38d
Education ≤Primary school 0.16±0.32a 0.17±0.31a 0.16±0.32a <0.001
Middle school 0.22±0.35b 0.23±0.34b 0.22±0.35b
High school 0.21±0.34b,c 0.22±0.33b,c 0.21±0.34b,c
≥College 0.19±0.32a,b,c,d 0.19±0.32a,b,c,d 0.19±0.32a,b,c,d
Household income quartile Low 0.28±0.38a 0.28±0.38a 0.28±0.38a <0.001
Low-middle 0.19±0.32b,c 0.19±0.32b,c 0.19±0.32b,c
High-middle 0.16±0.30c,d 0.16±0.29c 0.16±0.30c,d
High 0.14±0.29d 0.14±0.28b,c,d 0.14±0.29d
Dental Institutions Dental Clinic 0.19±0.33 0.20±0.32 0.19±0.33 0.500*
Dental Hospital 0.18±0.31 0.18±0.31 0.18±0.31

*P-value is measured by T-test,

P-value is measured by ANOVA.

a -dThe different letter indicates significant difference (P<0.05) in Scheffé's multiple comparison test, within same column.

Table 5.
Beta regression for prescribing rates
Variables Classification Model 1 (N=931) Model 2 ( N=3,836) Model 3 ( N=3,836) Model 4 ( N=3,836)
exp(b) P>|z| exp(b) P>|z| exp(b) P>|z| exp(b) P>|z|
Gender Female 0.907 0.093 0.895 0.009 0.702 0.020 0.896 0.014
Age ≤19 years 0.702 0.024 0.580 0.000 0.925 0.403 0.581 0.000
40-65 years 0.925 0.429 1.180 0.028 0.901 0.365 1.188 0.028
≥65 years 0.901 0.383 1.433 0.000 0.908 0.083 1.467 0.000
Martial status Unmarried 0.989 0.928 1.075 0.422 0.990 0.928 1.073 0.451
Divorced/Widowed/Separated 0.932 0.428 1.020 0.798 0.933 0.403 1.021 0.805
Education Middle school 0.886 0.152 1.044 0.489 0.886 0.130 1.052 0.446
High school 0.933 0.366 0.935 0.265 0.934 0.366 0.937 0.309
≥College 0.968 0.722 0.856 0.034 0.968 0.712 0.854 0.040
Economic Activity Non-Activity 0.927 0.204 1.059 0.262 0.927 0.196 1.067 0.231
Chronic Disease No 0.936 0.365 1.042 0.374 0.937 0.322 1.041 0.401
Household income Low-middle 0.981 0.796 0.876 0.026 0.981 0.792 0.88 0.042
quartile High-middle 1.016 0.835 0.831 0.003 1.016 0.831 0.833 0.005
High 0.860 0.078 0.786 0.000 0.860 0.060 0.791 0.000
Private Health Fixed benefit insured 1.023 0.729 1.017 0.747 1.023 0.727 1.017 0.758
Insurance Indemnity insured 1.129 0.242 1.029 0.681 1.128 0.228 1.023 0.751
5.63 1.669 0.448
AIC ―591.2548 ―8971.758 4561.914 ―28784.79
BIC ―504.2021 ―8859.218 4786.993 ―28672.25
Log likelihood 313.62738 4503.8788 ―2244.9571 14410.397
Proportion 33.89 28.7 37 29.38
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