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Lee and Lee: Acanthocytosis in a Patient with Chorea-acanthocytosis
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Diagnostic Hematology
Laboratory Medicine Online

Laboratory Medicine Online 2012; 2(3): 179-180.

Published online: 1 July 2012

DOI: https://doi.org/10.3343/lmo.2012.2.3.179

Acanthocytosis in a Patient with Chorea-acanthocytosis

Sun Min Lee, M.D.1, 3, Jae-Hyeok Lee, M.D.2, 3

1Department of Laboratory Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.

2Department of Neurology, Pusan National University Yangsan Hospital, Yangsan, Korea.

3Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.

Corresponding author: Jae-Hyeok Lee, M.D. Department of Neurology, and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, 20 Gumo-ro, Mulgum-up, Yangsan 626-770, Korea. Tel: +82-55-360-2453, Fax: +82-55-360-1880, drleejae@hanmail.net

Received 26 March 2012       Revised 23 April 2012       Accepted 1 May 2012

© 2012, Laboratory Medicine Online

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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lmo-2-179-g001
Fig. 1
Peripheral blood smear demonstrates many acanthocytes that do not have central pallor and are smaller than normocytic red blood cells (A) (Wright stain,×1,000). Scanning electron microscopy discloses many acanthocytes characterized by their thorn-like protrusions (B) (SEM,×1,000).

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Notes

This article is available from http://www.labmedonline.org

References

1. Walker RH, Jung HH, Dobson-Stone C, Rampoldi L, Sano A, Tison F, et al. Neurologic phenotypes associated with acanthocytosis. Neurology. 2007. 68:92–98.
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2. Storch A, Kornhass M, Schwarz J. Testing for acanthocytosis, A prospective reader-blinded study in movement disorder patients. J Neurol. 2005. 252:84–90.
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