Translation: Unexpected Hemoglobin A1c Results*

Alina-Gabriela Sofronescu; Laurie M. Williams; Dorinda M. Andrews; Yusheng Zhu

doi:10.3343/lmo.2011.1.2.1

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Sofronescu, Williams, Andrews, and Zhu: Translation: Unexpected Hemoglobin A1c Results*

Translation

Clinical Chemistry

Laboratory Medicine Online

Laboratory Medicine Online 2011; 1(2): 67-71.

Published online: 1 April 2011

DOI: https://doi.org/10.3343/lmo.2011.1.2.1

Translation: Unexpected Hemoglobin A_1c Results^*

Alina-Gabriela Sofronescu, Laurie M. Williams, Dorinda M. Andrews, Yusheng Zhu

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, USA.

Translator: Sun Min Lee. Department of Laboratory Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea. (yaong97@paran.com). This article is translated from an English language article, originally published in Clinical Chemistry under agreement between the publishers of Laboratory Medicine Online and Clinical Chemistry. Acknowledgement and other information that is not directly related to the content of the article has not been translated, and thus omitted in this article. References are listed as they were in the original work. Original copyright © 2011 American Association for Clinical Chemistry, Inc.

Received 11 March 2011 Revised 11 March 2011 Accepted 14 March 2011

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Figures and Tables

Fig. 1

CE-HPLC chromatogram for Hb A1c analysis. Hb S and an aberrant Hb A_1c value of 115.8% represented the predominant Hb peaks in the chromatogram.

Fig. 2

Chromatogram of Hb variants analysis with the CE-HPLC β-Thalassemia Short Program. Hb S (37.4%), wild-type Hb A2 (3.2%), and Hb F (<1.0%) were identified, but Hb A was not detected. A large peak, which we designated P2, was detected at 53.0%.

Notes

This article is available from http://www.labmedonline.org

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