Journal List > Kosin Med J > v.30(1) > 1057058

Kosin Med J. 2015 Jun;30(1):69-72. Korean.
Published online June 30, 2015.  https://doi.org/10.7180/kmj.2015.30.1.69
Copyright © 2015 Kosin University College of Medicine
A Case of Focal Segmental Glomerulosclerosis in Turner Syndrome
A Rum Han,1 Young Ki Lee,1 Hyun Yon Jung,1 Jae Hyun Park,1 Jung-Woo Noh,1 and Eun Suk Nam2
1Department of Internal Medicine, and Hallym Kidney Research Institute Hallym University College of Medicine, Seoul, Korea.
2Department of Pathology, Hallym University College of Medicine, Seoul, Korea.

Corresponding Author: Young Ki Lee, Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University, 1, Singil-ro, Yeongdeungpo-gu, Seoul, 150-950, Korea. TEL: +82-2-829-5214, FAX: +82-2-846-4669, Email: km2071@unitel.co.kr
Received February 13, 2014; Revised March 30, 2014; Accepted April 23, 2014.

Abstract

Turner syndrome is usually accompanied with various anomalies. Congenital urological and renal abnormalities are often associated with this syndrome. The occurrence of glomerulonephritis is uncommon. An 18-year-old woman showed fatigue and profound proteinuria. She had been diagnosed with Turner syndrome in her age of 15. The kidney biopsy specimen examined by light microscopy, immunofluorescence and electron microscopic examination revealed focal segmental glomerulosclerosis. This is the first case report of focal segmental glomerulosclerosis in turner syndrome in South Korea.

Keywords: Focal Segmental; Glomerulosclerosis; Proteinuria; Turner syndrome

Figures


Fig. 1
Jone-silver stain reveals segmental sclerosis in two glomeruli and tubular atrophy and interstitial foam cells(A, ×200). Electron microscopy displays diffuse effacement of foot processes. There is no electron dense material deposit(B).
Click for larger image

Tables


Table 1
Six cases of Turner syndrome with glomerulonephritis
Click for larger image

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