Systemic Review for The Effectiveness of Current Conservative Treatment in Necrotizing Pancreatitis

Jungik Park; Ungseok Yang

doi:10.7180/kmj.2014.29.1.11

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Park and Yang: Systemic Review for The Effectiveness of Current Conservative Treatment in Necrotizing Pancreatitis

Review Article

Kosin Medical Journal 2014;29(1):11-16.

Published online: 17 December 2014

DOI: https://doi.org/10.7180/kmj.2014.29.1.11

Systemic Review for The Effectiveness of Current Conservative Treatment in Necrotizing Pancreatitis

Jungik Park¹, Ungseok Yang²

¹Department of Internal Medicine, Dong-eui Medical Center, Busan, Korea

²Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea

Corresponding Author: Ungseok Yang, Department of Internal Medicine, Pusan National University, 179, Gudeok-ro, Seo-gu, Busan, Korea TEL: +82-51-865-0067 FAX: +82-51-865-8002 E-mail: usyang112@gmail.com

Received 17 October 2013 Revised 12 December 2013 Accepted 27 December 2013

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The standard treatment of pancreatic necrosis has been surgical necrosectomy. There has been debate on whether early surgical intervention can reduced by infected pancreatic necrosis (IPN). Early emergency laparotomy and multiple organ failure remain associated with high mortality. However, reports have presented during the last 10 years of survival of severe acute pancreatitis with medical management. Large and multicenter study showed that about two thirds of patients with necrotizing pancreatitis can be treated conservatively with relatively low mortality. Patients with IPN benefit from postponding intervention and minimal invasive treatment. We reviewed 4 literatures including 2 Korean institute reseached reports concerning non-surgical, conservative treatments of necrotizing pancreatitis including IPN. Large and multicenter study showed that about two thirds of patients with necrotizing pancreatitis can be treated conservatively with relatively low mortality.

Keywords: Acute pancreatitis, Infection, Necrosis, Treatment

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