A Case of Type III Autoimmune Polyglandular Syndrome

Sangeon Gwoo; Young Sik Choi; Bu Kyung Kim; Yo Han Park; Keun Tae Kim; Jun Seop Lee

doi:10.7180/kmj.2013.28.2.167

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Gwoo, Choi, Kim, Park, Kim, and Lee: A Case of Type III Autoimmune Polyglandular Syndrome

Case Report

Kosin Medical Journal 2013;28(2):167-170.

Published online: 19 January 2013

DOI: https://doi.org/10.7180/kmj.2013.28.2.167

A Case of Type III Autoimmune Polyglandular Syndrome

Sangeon Gwoo, Young Sik Choi, Bu Kyung Kim, Yo Han Park, Keun Tae Kim, Jun Seop Lee

Department of Internal Medicine, College of Medicine, Kosin University, Busan, Korea

Corresponding author: Young Sik Choi, Department of Internal medicine, College of Medicine, Kosin University, 34 Amnamdong, Seo-gu, Busan, 602-702, Korea TEL: +82-51-990-6102 FAX: +82-51-990-3005 E-mail: yschoi@kosinmed.or.kr

Received 23 February 201226 March 2012 Accepted 20 April 2012

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The autoimmune polyglandular syndromes (APS) are groups of syndromes comprising a combination of endocrine and nonendocrine autoimmune diseases. Among of those four types of APS, the main characteristics of the 3 APS are autoimmune thyroid diseases associated to other autoimmune diseases, excluding Addison’s disease. Type 3 APS are also subdivided into 3A, 3B, 3C, and 3D. Recently, we experience a case of APS manifesting 3A, 3C, and 3D subtype. A 28-year-old woman developed type I diabetes. According to her medical history, she had Graves’ disease, vitiligo, auimmune hemolytic anemia and systemic lupus erythematosus (SLE). The antoantibodies associated with Graves’ disease, SLE, and type I diabetes showed positive findings. We report this case with literatures review.

Keywords: Autoimmune polyglandular syndromes, Graves’ disease, Systemic lupus erythematosus, Type I diabetes

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Fig. 1.

Thyroid scan showed diffuse uptake of radio iodine.

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