Journal List > J Korean Thyroid Assoc > v.6(1) > 1056545

J Korean Thyroid Assoc. 2013 May;6(1):75-79. Korean.
Published online May 31, 2013.  https://doi.org/10.11106/jkta.2013.6.1.75
Copyright © 2013. the Korean Thyroid Association. All rights reserved.
Two Cases of Postpartum Thyroiditis Followed by Graves' Disease
Ji Hoon Yang, Eun Jin Han and Chang Hoon Yim
Department of Internal Medicine, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine, Seoul, Korea.

Correspondence: Chang Hoon Yim, MD, PhD, Department of Internal Medicine, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine, 1-19 Mukjeong-dong, Jung-gu, Seoul 100-380, Korea. Tel: 82-2-2000-4719, Fax: 82-2-2000-7147, Email: changhoon.yim@cgh.co.kr
Received September 22, 2012; Revised April 12, 2013; Accepted April 22, 2013.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Abstract

The most common thyroid dysfunctions that occur after delivery are postpartum thyroiditis (PPT) and Graves' disease (GD). PPT is more likely to occur among patients who had a history of PPT or GD. For that reason, it is possible to assume that both PPT and GD occur concomitantly after delivery. Here we report two cases of atypical postpartum thyroid dysfunctions presenting the simultaneous occurrence of PPT and GD. A 31-year-old woman with history of PPT had thyrotoxicosis and hypothyroidism of PPT followed by GD with mild symptoms. The patient recovered quickly afterwards. In the second case, a 28-year-old woman with a history of GD presented with thyrotoxicosis of PPT followed by severe GD. The patient required long-term antithyroid treatment.

Keywords: Graves' disease; Postpartum thyroiditis; Thyrotoxicosis

Figures


Fig. 1
Serum free T4 and TBII change during postpartum period. The dosages of LT4 (levothyroxine) or PTU (propylthiouracil) are shown at the top. (A) Case 1, (B) Case 2.
Click for larger image

Tables


Table 1
Summary of laboratory test results in case 1
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Table 2
Summary of laboratory test results in case 2
Click for larger image

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