A clinical evaluation of safety of an office bleaching gel containing 30% hydrogen peroxide

Sin-Young Kim; Je-Uk Park; Chang-Hyen Kim; Sung-Eun Yang

doi:10.5395/JKACD.2010.35.3.198

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Kim, Park, Kim, and Yang: A clinical evaluation of safety of an office bleaching gel containing 30% hydrogen peroxide

Basic Research

Journal of Korean Academy of Conservative Dentistry

Journal of Korean Academy of Conservative Dentistry 2010; 35(3): 198-210.

Published online: 31 May 2010

DOI: https://doi.org/10.5395/JKACD.2010.35.3.198

A clinical evaluation of safety of an office bleaching gel containing 30% hydrogen peroxide

Sin-Young Kim¹, Je-Uk Park², Chang-Hyen Kim², Sung-Eun Yang¹

¹Department of Conservative Dentistry, Seoul St. Mary's Hospital, Catholic University of Korea, Korea.

²Department of Oral and Maxillofacial Surgery, Seoul St. Mary's Hospital, Catholic University of Korea, Korea.

Correspondence to: Sung-Eun. Yang Department of Conservative Dentistry Seoul St. Mary's Hospital, Catholic University of Korea 505, Banpo-dong, Seocho-gu, Seoul, 137-044, Korea. Tel: 82-2-2258-6296, Fax: 82-2-537-2374, dentyeun@catholic.ac.kr

Received 21 April 2010 Revised 26 April 2010 Accepted 29 April 2010

Abstract

This study evaluated the safety of an office bleaching gel (RemeWhite, Remedent Inc., Deurle, Belgium) containing 30% hydrogen peroxide. 37 volunteers were recieved office bleaching with the RemeWhite for 3 times at one visit, total 2 visits. As control group, the same gel in which hydrogen peroxide was not included was applied to 34 volunteers with the same protocol.

There was no difference between experimental group and control group using electric pulp test. In the result of gingival inflammation index and tooth sensitivity test, there was mild pain response in experimental group but it disappeared as time went by. Therefore, safety of the office bleaching gel containing 30% hydrogen peroxide was confirmed.

Keywords: Office bleaching gel, Safety, Hydrogen peroxide, Clinical study

Figures and Tables

Table 1

Experimental protocol of randomized clinical trial

Table 2

Age and gender of the participants in the study

Table 3

Changes of EPT (Electric pulp test)

1) Two sample t-test

2) Wilcoxon's rank sum test

^*p < 0.05

Table 4

Changes of GI (gingival inflammation index)

1) McNemar's test

2) N/A: Not Applicable

^*: p < 0.05

Table 5

Tooth sensitivity at each visit

1) McNemar's test

^*: p < 0.05

Table 6

Percentage of abnormal response

1) Chi-square test

Table 7

Changes of vital sign

1) two sample t-test

2) Wilcoxon's rank sum test

^*: p < 0.05

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