Effect of local anesthesia on pulpal blood flow in mechanically stimulated teeth

Wan-Sik Chu; Seung-Ho Park; Dong-Kuk Ahn; Sung Kyo Kim

doi:10.5395/JKACD.2006.31.4.257

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Chu, Park, Ahn, and Kim: Effect of local anesthesia on pulpal blood flow in mechanically stimulated teeth

Original Article

J Korean Acad Conserv Dent 2006;31(4):257-262.

Published online: 14 January 2006

DOI: https://doi.org/10.5395/JKACD.2006.31.4.257

Effect of local anesthesia on pulpal blood flow in mechanically stimulated teeth

Wan-Sik Chu, Seung-Ho Park, Dong-Kuk Ahn¹, Sung Kyo Kim^*

Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea

¹Department of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu, Korea

^*Corresponding Author: Sung Kyo Kim, Department of Conservative Dentistry, School of Dentistry, Kyungpook National University 188-1, Samdeok-Dong, 2-Ga, Jung-Gu, Daegu, Korea, 700-412, Tel: 82-53-420-5935 Fax: 82-53-426-8958, E-mail: skykim@knu.ac.kr

Received 23 August 2005 Revised 24 January 2006 Accepted 9 February 2006

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aims of the study were to evaluate the effect of epinephrine-containing local anesthetics on pulpal blood flow (PBF) and to investigate its effect on cavity preparation-induced PBF change. PBF was recorded using a laser Doppler flowmeter (Perimed Co., Sweden) from canines of nine cats under general anesthesia before and after injection of local anesthetics and after cavity preparation. 2% lidocaine hydrochloride with 1 : 100,000 epinephrine was administered by local infiltration given apical to the mandibular canine at the vestibular area and the same volume of isotonic saline was injected on the contralateral tooth as a control. A round carbide bur was operated at slow speed with isotonic saline flushing to grind spherical cavities with increasing depth through the enamel and into the dentin on both teeth. The obtained data was analyzed with paired t-test.

Cavity preparation caused significant increase of PBF (n = 9, p < 0.05). Local infiltration of lidocaine with epinephrine resulted in decreases of PBF (n = 9, p < 0.05), whereas there was no significant change of PBF with the physiologic saline as a control. Cavity preparation on tooth anesthetized with lidocaine with epinephrine caused significantly less increase of PBF than in control tooth (p < 0.05).

Therefore, the result of the present study demonstrates that local infiltration of 2% lidocaine with 1 : 100,000 epinephrine effectively reduces PBF increase caused by cavity preparation.

Keywords: Pulpal blood flow, Epinephrine, Lidocaine, Cavity preparation, Local anesthetics, Neurogenic inflammation

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Figure 1.

Schematic drawing of devices used to record pulpal blood flow.

Figure 2.

Changes in pulpal blood flow in response to the cavity preparation.

Figure 3.

Changes in pulpal blood flow PBF in response to local infiltration of 2% lidocaine with 1 : 100,000 epinephrine (mean ± SEM).

*Statistically significant in paired t-test (p < 0.05).

Figure 4.

Changes in pulpal blood flow PBF in response to cavity preparation (mean ± SEM).

*Statistically significant in paired t-test (p < 0.05).

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