Antibiotic susceptibility in mutans streptococci and Streptococcus anginosus isolated from dental plaque

Joong-Ki Kook; Sang-Soo Lim; So Young Yoo; Ho-Keel Hwang

doi:10.5395/JKACD.2004.29.5.462

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Kook, Lim, Yoo, and Hwang: Antibiotic susceptibility in mutans streptococci and Streptococcus anginosus isolated from dental plaque

Original Article

Journal of Korean Academy of Conservative Dentistry

Journal of Korean Academy of Conservative Dentistry 2004; 29(5): 462-469.

Published online: 30 September 2004

DOI: https://doi.org/10.5395/JKACD.2004.29.5.462

Antibiotic susceptibility in mutans streptococci and Streptococcus anginosus isolated from dental plaque

Joong-Ki Kook^1,³, Sang-Soo Lim^2,³, So Young Yoo^1,³, Ho-Keel Hwang^2,³

¹Department of Oral Biochemistry, College of Dentistry, Chosun University, Korea.

²Department of Conservative Dentistry, College of Dentistry, Chosun University, Korea.

³Oral Biology Research Institute, College of Dentistry, Chosun University, Korea.

Corresponding author: Ho-Keel Hwang. Department of Conservative Dentistry, and Oral Biology Research Institute, College of Dentistry, Chosun University 375 Seo-suk Dong, Dong-Gu, Gwang-ju, Korea, 501-749. Tel: 82-62-220-3846, Fax: 82-62-232-9064, rootcanal@hanmail.net

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of this study was to investigate the susceptibility of mutans streptococci (S. mutans and S. sobrinus) and Streptococcus anginosus, for seven antibiotics, penicillin G, amoxicillin, ciprofloxacin, cefuroxime, erythromycin, bacitracin, and vancomycin. The minimum inhibitory concentration (MIC) of seven antibiotics against 3 species (type strains) of mutans streptococci and S. anginosus, 10 strains (wild type) of S. mutans, 7 strains (wild type) of S. sobrinus, and 11 strains (wild type) of S. anginosus, were measured by broth dilution method. All of the type strains of mutans streptococci and S. anginosus had the same susceptibility for penicillin G, amoxicillin, cefuroxime and bacitracin. Type strain of S. anginosus was sensitive in ciprofloxacin, but those of mutans streptococci were not. All of the clinical isolates of mutans streptococci and S. anginosus had the same susceptibility for the seven antibiotics. Our data reveal that mutans streptococci and S. anginosus have similar antibiotic-resistant character. In addition, these results may offer the basic data to verify the antibiotic-resistant mechanism of mutans streptococci and S. anginosus.

Keywords: Antibiotics, Mutans streptococci, S. anginosus, Susceptibility

Figures and Tables

Table 1

Bacteria strains used in this study

^*Department of Oral Biochemistry, College of Dentistry, Chosun University

( )^**Older-name

Table 2

Interpretive table for biotyping of mutans streptococci8,9)

^*Aerobically at 37℃ for 48 h.

Table 3

Interpretive standards for dilution susceptibility testing11)

Table 4

Biochemical test of S. anginosus isolated on MSB agar

^*Aerobically at 37℃ for 48 h.

^**Department of Oral Biochemistry, College of Dentistry, Chosun University

Table 5

Minimum inhibitory concentration of antibiotics against mutans streptococci and S. anginosus

¹Penicillin G, ²Amoxicillin, ³Ciprofloxacin, ⁴Cefuroxime, ⁵Erythromycin, ⁶Bacitracin, ⁷Vancomycin

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