Abstract
The effects of alcohol consumption on diabetic patients are still unclear and inconclusive. Generally, light-to-moderate alcohol consumption (< 3 glasses) may have beneficial effects without disturbing glucose control. However, excessive alcohol consumption may have harmful effects such as hypoglycemia, impaired glucose control, metabolic dysregulation, and increased risk of diabetic complications. This review focused on the relationship between alcohol consumption and diabetic mellitus and effect of alcohol on diabetic patients. Based on previous results, we propose a theory of proper alcohol consumption in diabetic patients.
References
1. Corrao G, Bagnardi V, Zambon A, La Vecchia C. A metaanalysis of alcohol consumption and the risk of 15 diseases. Prev Med. 2004; 38:613–9.
2. Bagnardi V, Blangiardo M, La Vecchia C, Corrao G. A metaanalysis of alcohol drinking and cancer risk. Br J Cancer. 2001; 85:1700–5.
3. Dyer AR, Stamler J, Paul O, Berkson DM, Shekelle RB, Lepper MH, McKean H, Lindberg HA, Garside D, Tokich T. Alcohol, cardiovascular risk factors and mortality: the Chicago experience. Circulation. 1981; 64(III):20–7.
4. Carlsson S, Hammar N, Grill V. Alcohol consumption and type 2 diabetes metaanalysis of epidemiological studies indicates a U-shaped relationship. Diabetologia. 2005; 48:1051–4.
5. Koppes LL, Dekker JM, Hendriks HF, Bouter LM, Heine RJ. Moderate alcohol consumption lowers the risk of type 2 diabetes: a metaanalysis of prospective observational studies. Diabetes Care. 2005; 28:719–25.
6. Korea Ministry of Health and Welfare & Korea Centers for Disease Control and Prevention. Korea Health Statistics 2012: Korea National Health and Nutrition Examination Survey (KNHANESV-3). Cheongwon: Korea Centers for Disease Control and Prevention;2014. p. 27–8.
7. Howard AA, Arnsten JH, Gourevitch MN. Effect of alcohol consumption on diabetes mellitus: a systematic review. Ann Intern Med. 2004; 140:211–9.
8. Holbrook TL, Barrett-Connor E, Wingard DL. A prospective population-based study of alcohol use and non-insulindependent diabetes mellitus. Am J Epidemiol. 1990; 132:902–9.
9. Seike N, Noda M, Kadowaki T. Alcohol consumption and risk of type 2 diabetes mellitus in Japanese: a systematic review. Asia Pac J Clin Nutr. 2008; 17:545–51.
10. Ajani UA, Hennekens CH, Spelsberg A, Manson JE. Alcohol consumption and risk of type 2 diabetes mellitus among US male physicians. Arch Intern Med. 2000; 160:1025–30.
11. Siler SQ, Neese RA, Christiansen MP, Hellerstein MK. The inhibition of gluconeogenesis following alcohol in humans. Am J Physiol. 1998; 275:E897–907.
12. Vrij-Standhardt WG. Effects of alcohol on the metabolism of macronutrients. Van der Heij DG, Schaafsma G, editors. Biomedical and social aspects of alcohol use: a review of the literature. Pudoc: Wageningen;1995. p. 62–71.
14. van den Berg H, van der Gaag M, Hendriks H. Influence of lifestyle on vitamin bioavailability. Int J Vitam Nutr Res. 2002; 72:53–9.
15. Halsted CH, Villanueva JA, Devlin AM, Chandler CJ. Metabolic interactions of alcohol and folate. J Nutr. 2002; 132:2367S–72S.
16. Mukamal KJ, Robbins JA, Cauley JA, Kern LM, Siscovick DS. Alcohol consumption, bone density, and hip fracture among older adults: the cardiovascular health study. Osteoporos Int. 2007; 18:593–602.
17. Bush K, Kivlahan DR, McDonell MB, Fihn SD, Bradley KA. The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test. Arch Intern Med. 1998; 158:1789–95.
18. Park J, Kweon S, Kim Y, Jang MJ, Oh K. Dietary behaviors related to metabolic syndrome in Korean adults. Korean J Community Nutr. 2012; 17:664–75.
19. Pearson TA, Blair SN, Daniels SR, Eckel RH, Fair JM, Fortmann SP, Franklin BA, Goldstein LB, Greenland P, Grundy SM, Hong Y, Miller NH, Lauer RM, Ockene IS, Sacco RL, Sallis JF Jr, Smith SC Jr, Stone NJ, Taubert KA. American Heart Association Science Advisory and Coordinating Committee. AHA guidelines for primary prevention of cardiovascular disease and stroke: 2002 update: consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseases. Circulation. 2002; 106:388–91.
20. Korean Dietetic Association. Liver, gallbladder and pancreatitis disease. Korean Dietetic Association. Manual of medical nutrition therapy. 3rd ed.Seoul: Medrang;2008. p221.