Journal List > J Korean Diabetes > v.17(3) > 1055026

Park, Kang, Park, Ahn, Shin, Lee, Cho, Hwang, Ahn, Chung, and Jeong: A Case of Actinomycosis of an Orbital Subperiosteal Abscess in a Patient with Type 2 Diabetes Mellitus

Abstract

Orbital and paranasal actinomycosis have not been commonly reported. We report a case of this uncommon infection, which was improved after endonasal endoscopic drainage and antibiotics. A 53-year-old woman with type 2 diabetes mellitus complained of inability to lift her right upper eyelid and painful swelling over the preceding two days. Broad-spectrum antibiotics did not resolve her lesion. In ophthalmic examination, decreased visual acuity, upper and medial gaze limitation, and a relative afferent pupillary defect of her right eye were observed. Computed tomography of the orbit showed aggravated orbital cellulitis, preseptal cellulitis, subperiosteal abscess, and maxillary and ethmoid sinusitis. After endonasal endoscopic drainage and systemic antibiotics, her clinical symptoms dramatically improved. Microbiological analysis of the maxillary excisional biopsy showed Actinomycosis. This case is of interest due to the rare orbital presentation of actinomycosis infection and the importance of appropriate surgical drainage and long-term antibiotics treatment in such cases. Because delayed diagnosis and treatment of rhino-orbital actinomycosis can cause permanent vision loss or intracranial abscess, it requires careful clinical attention.

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Fig. 1.
Right orbital ptosis and reddish swelling of the upper lid on presentation due to right orbital cellulitis.
jkd-17-219f1.tif
Fig. 2.
Orbital computed tomography scan showed preseptal cellulitis, ethmoidal sinusitis, maxillary sinusitis, and a subperiosteal abscess on the right side.
jkd-17-219f2.tif
Fig. 3.
(A) Microbiological analysis of the nasal abscess showed a small cluster of Actinomycosis with surrounding mixed inflammation and Splendore-Hoeppli phenomenon (arrowheads), (B) filamentous Actinomyces (arrows). (A) H&E, ×100, (B) Gomori Methenamine silver stain, ×400.
jkd-17-219f3.tif
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