Journal List > J Korean Diabetes > v.17(3) > 1055025

Jang, Kim, Bang, Jung, Jin, Jeong, Kim, and Kang: A Case of Acute Hyperglycemia Induced by Jerusalem Artichoke in a Patient with Type 2 Diabetes Mellitus

Abstract

Jerusalem artichoke (JA) mainly consists of inulin. In many experimental studies, inulin has been shown to be beneficial for decreasing glucose level. Therefore, JA is lately attracting wide attention as an anti-diabetic food. Therefore, many patients ingest JA in extract form. However, there are no published clinical studies in patients with diabetes to demonstrate benefit from the use of inulin-type fructans. We experienced a diabetes inpatient with acute hyperglycemia associated with JA. We could not control the patient's blood glucose in spite of addition and increment of insulin. We found that she had taken extracts of JA and recommended cessation. After discontinuing JA extracts, her blood glucose was well controlled in spite of discontinuation of insulin. Thus, in this patient, JA had actually increased blood glucose. We suggest that JA may be dangerous for use in diabetic patients.

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Table 1.
Capillary plasma glucose of the patient, measured by a glucometer
Admission date Time Sugar (mg/dL) Dose of glargine (unit) Admission date Time Sugar (mg/dL) Dose of glargine (unit)
1 day PP2 (L) 374   9 day Fasting 150 30
  PP2 (S) 355     PP2 (B) 188  
2 day Fasting 266 12   PP2 (L) 280  
  PP2 (B) 285     PP2 (S) 287  
  PP2 (L) 410   12 day Fasting 126 26
  PP2 (S) 294     PP2 (B) 305  
3 day Fasting 296 22   PP2 (L) 177  
  PP2 (B) 323     PP2 (S) 212  
  PP2 (L) 301   15 day Fasting 113 22
  PP2 (S) 302     PP2 (B) 132  
4 day Fasting 257 26   PP2 (L) 105  
  PP2 (B) 326     PP2 (S) 80  
  PP2 (L) 332   16 day Fasting 169 16
  PP2 (S) 284     PP2 (B) 117  
5 day Fasting 264 30   PP2 (L) 113  
  PP2 (B) 331     PP2 (S) 129  
  PP2 (L) 308   17 day Fasting 72 16
  PP2 (S) 355     PP2 (B) 175  
6 day Fasting 219 34   PP2 (L) 144  
  PP2 (B) 332     PP2 (S) 127  
  PP2 (L) 339   18 day Fasting 80 Stop
  PP2 (S) 289     PP2 (B) 118  
7 day Fasting 169 38   PP2 (L) 306  
  PP2 (B) 271     PP2 (S) 105  
  PP2 (L) 301   19 day Fasting 140  
  PP2 (S) 274     PP2 (B) 185  
8 day Fasting 207 38   PP2 (L) 287  
  PP2 (B) 311     PP2 (S) 158  
  PP2 (L) 247   20 day Fasting 165  
  PP2 (S) 310 Stop eating JA        

JA, Jerusalem artichoke; PP2 (B), postprandial 2 hours (breakfast); PP2 (L), postprandial 2 hours (lunch); PP2 (S), postprandial 2 hours (supper).

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