Journal List > J Korean Diabetes > v.17(3) > 1055015

J Korean Diabetes. 2016 Sep;17(3):155-158. Korean.
Published online September 30, 2016.
Copyright © 2016 Korean Diabetes Association
Sleep and Diabetes
Eun Yeon Joo
Sleep Clinic, Department of Neurology, Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Corresponding author: Eun Yeon Joo. Sleep Clinic, Department of Neurology, Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea. Email:
Received July 20, 2016; Accepted August 11, 2016.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Sleep is a physiologic state of decreased metabolism and serves a reparative role, marked by increased glycogen stores and peptide synthesis. Normal sleep is characterized by reduced glucose turnover by the brain and other metabolically active tissues, particularly during non-rapid eye movement sleep. Circadian and sleep-related changes in glucose tolerance occur in normal subjects. Sleep duration has decreased over the last several decades, and with this have come cross-sectional and longitudinal data suggesting a link between short sleep duration and the prevalence of type 2 diabetes. Forced decreased sleep duration in healthy individuals has linked to impaired glucose homeostasis. Moreover, short sleep duration has been associated with obesity. Obstructive sleep apnea syndrome is characterized by diminished or abrogated airflow, which results in intermittent hypoxia and sleep fragmentation. This disorder appears to be associated with impaired glucose tolerance. Thus, the quality and quantity of sleep may have a profound effect on type 2 diabetes; therefore, these relationships should be carefully assessed in primary and endocrinology clinics.

Keywords: Diabetes mellitus; Obstructive sleep apnea; Sleep; Sleep deprivation

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